Evidence map›Paper›PMID 34898381›Full record

ArticleHuman vaccines & immunotherapeutics2021

Heterologous prime-boost vaccination against COVID-19: is it safe and reliable?

Om Prakash Choudhary, Priyanka, Jivan Q Ahmed, Teroj A Mohammed, Indraj Singh, Alfonso J Rodriguez-Morales

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Strategies and safety considerations of booster vaccination in COVID-19.Bosnian journal of basic medical sciences · 2022
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Om Prakash ChoudharyDepartment of Veterinary Anatomy and Histology, College of Veterinary Sciences and Animal Husbandry, Central Agricultural University (I), Selesih, Aizawl, India.ORCID 0000-0001-6929-675X
PriyankaIndependent Researcher, 07, Type IV Quarter, College of Veterinary Sciences and Animal Husbandry, Central Agricultural University (I), Selesih, Aizawl, India.ORCID 0000-0003-4039-0157
Jivan Q AhmedDepartment of Pathology and Microbiology, College of Veterinary Medicine, University of Duhok, Duhok, Iraq.
Teroj A MohammedDental Basic Science Department, College of Dentistry, University of Duhok, Duhok, Iraq.ORCID 0000-0002-9538-9789
Indraj SinghCommunity Health Centre, Deoband, Saharanpur, India.
Alfonso J Rodriguez-MoralesGrupo de Investigacion Biomedicina, Faculty of Medicine, Fundacion Universitaria Autonoma de las Americas, Pereira, Colombia.ORCID 0000-0001-9773-2192

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Throughout the globe, many nations are struggling to cope with the consecutive waves of the COVID-19. Several vaccines have been employed to overcome this ongoing pandemic and are available as single and double-dose inoculations; however, homologous vaccine efficacy is being reconsidered due to the rapidly emerging SARS-CoV-2 variants. Many studies have been conducted on the heterologous prime-boost vaccine regimens and have shown good efficacy results against COVID-19. This article aims to highlight the safety and reliability of heterologous prime-boost vaccination against COVID-19. We have also made some recommendations towards using these combinations of vaccines for the global mitigation of the subsequent waves of COVID-19.

Indexed as

COVID-19Antibodies, ViralCOVID-19 VaccinesHumansImmunization, SecondaryImmunogenicity, VaccineReproducibility of ResultsSARS-CoV-2VaccinationAntibodies, ViralCOVID-19 VaccinescocktailCOVID-19efficacyimmunogenicityrecommendationsSARS-CoV-2vaccine

Identifiers

PMID34898381
PMCPMC8726007

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.