Evidence map›Paper›PMID 34898380›Full record

ArticleBioengineered2022

Trametes robiniophila represses angiogenesis and tumor growth of lung cancer via strengthening let-7d-5p and targeting NAP1L1.

HuiZhu Gan, XinXin Xu, YinYin Bai

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. A New Role of NAP1L1 in Megakaryocytes and Human Platelets.International journal of molecular sciences · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

HuiZhu GanDepartment of Hematology and Oncology, China-Japan Union Hospital of Jilin University, Changchun City, JiLin Province, China.
XinXin XuDepartment of Hematology and Oncology, China-Japan Union Hospital of Jilin University, Changchun City, JiLin Province, China.
YinYin BaiDepartment of Hematology and Oncology, China-Japan Union Hospital of Jilin University, Changchun City, JiLin Province, China.
Jilin University · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trametes robiniophila (Huaier) is available to refrain lung cancer (LC) cell progression, but its impact and mechanism on angiogenesis of LC are not proved. The study was to explore the potential mechanism of Huaier repressing angiogenesis and tumor growth in LC via strengthening let-7d-5p and targeting NAP1L1. Let-7d-5p and NAP1L1 expression was detected in LC tissues and cells (A549). Pretreatment of A549 cells was with Huaier. Transfection of changed let-7d-5p and NAP1L1 was to A549 cells to uncover their roles in LC cell progression with angiogenesis. Evaluation of the impact of let-7d-5p on angiogenesis in LC was

Indexed as

Lung NeoplasmsA549 CellsAnimalsApoptosisComplex MixturesFemaleHumansLungMiceMice, NudeMicroRNAsNeovascularization, PathologicNucleosome Assembly Protein 1TrametesComplex MixtureshuaierMicroRNAsmirnlet7 microRNA, humanNAP1L1 protein, humanNucleosome Assembly Protein 1angiogenesislet-7d-5plung cancerNAP1L1Trametes robiniophila

Identifiers

PMID34898380
PMCPMC8973683
OpenAlexW4200494383

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.