Evidence map›Paper›PMID 34898359›Full record

ArticleBioengineered2022

Effect of Taspine hydrochloride on the repair of rat skin wounds by regulating keratinocyte growth factor signal.

Xiumei Wang, Yang Gao, Xiaochen Sun

Open access · goldAbstract readVideo-Audio Media
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Effect ofVeterinary and animal science · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Xiumei WangDepartment of Dermatology, Liaocheng People's Hospital, Liaocheng, China.
Yang GaoDepartment of Plastic & Cosmetic Surgery, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiaochen SunDepartment of Dermatology, People's Hospital of Lixia District of Jinan, Jinan, China.
Chongqing Medical University · CNLiaocheng People's Hospital · CNThe People's Hospital of LinXia · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore the regulation of keratinocyte growth factor (KGF) in the process of repairing rat skin wounds by taspine hydrochloride (TA/HCl), 45 male Sprague-Dawley (SD) rats were purchased and divided into an experimental group, a dimethyl sulfoxide (DMSO) control group, and a basic fibroblast growth factor (bFGF) control group, each with 15 only. A back trauma model was innovatively adopted to prevent rats from biting and contaminating. The wound healing time and healing rate of the rat, and the Hydroxyproline (Hyp) and KGF expressions were observed. Morphological changes of wound tissue and the number of capillaries were observed after hematoxylin-eosin (HE) staining. The results showed that wound healing rate of experimental group and bFGF group was significantly higher than that of DMSO group (

Indexed as

SkinWounds and InjuriesAlkaloidsAnimalsFibroblast Growth Factor 7MaleRatsRats, Sprague-DawleySignal TransductionWound HealingAlkaloidsFgf7 protein, ratFibroblast Growth Factor 7taspinecapillariesgranulation tissuekeratinocyte growth factor signalskin woundsTaspine hydrochloride

Identifiers

PMID34898359
PMCPMC8805989
OpenAlexW4200622407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.