Evidence map›Paper›PMID 34898295›Full record

ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

The Impact of Anticoagulant Activity of Tissue Factor Pathway Inhibitor Measured by a Novel Functional Assay for Predicting Deep Venous Thrombosis in Trauma Patients: A Prospective Nested Case-Control Study.

Xiangyu Cao, Yu Su, Wenjie Zhang, Huiru Zhao, Meng Wen, Shan Lu, Yujing Zhao, Yuying Chen, Lei Liu, Xinwei Zang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Observational
  7. Hepatocyte-derived Microparticles as Novel Biomarkers for the Diagnosis of Deep Venous Thrombosis in Trauma Patients.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Xiangyu CaoPeking University Fourth School of Clinical Medicine, Beijing, China.
Yu Su66526Beijing Jishuitan Hospital, Beijing, China.
Wenjie Zhang66526Beijing Jishuitan Hospital, Beijing, China.
Huiru Zhao66526Beijing Jishuitan Hospital, Beijing, China.
Meng Wen66526Beijing Jishuitan Hospital, Beijing, China.
Shan Lu66526Beijing Jishuitan Hospital, Beijing, China.
Yujing Zhao66526Beijing Jishuitan Hospital, Beijing, China.
Yuying ChenBeijing 74639Chao-Yang Hospital, Capital Medical University, Beijing, China.
Lei LiuWuhan Third Hospital, Hubei, China.
Xinwei ZangPeking University Fourth School of Clinical Medicine, Beijing, China.
Jun WuPeking University Fourth School of Clinical Medicine, Beijing, China.ORCID https://orcid.org/0000-0001-5178-0906
Peking University · CNCapital Medical University · CNWuhan Third Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDeep venous thrombosis (DVT) is a common complication in patients with traumatic injury. Tissue factor pathway inhibitor (TFPI) is a natural anticoagulant protein in the extrinsic coagulation pathway. However, the relationship between DVT after trauma and the anticoagulant activity of TFPI remains unclear. In this prospective study, we investigated the role of TFPI in trauma patients with DVT to evaluate whether the anticoagulant activity of TFPI measured by a new functional assay can be used to help predict the risk of DVT.

Indexed as

AdultAgedAged, 80 and overAnticoagulantsBiomarkersBlood CoagulationCase-Control StudiesFemaleFollow-Up StudiesHospitalizationHumansLipoproteinsMaleMiddle AgedProspective StudiesROC CurveAnticoagulantsBiomarkerslipoprotein-associated coagulation inhibitorLipoproteinsanticoagulant activitydeep venous thrombosistissue factor pathway inhibitortrauma

Identifiers

PMID34898295
PMCPMC8671677
OpenAlexW4200148311

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.