Evidence map›Paper›PMID 34898280›Full record

ArticleMolecular and cellular biology2022

Histone Chaperone Nucleophosmin Regulates Transcription of Key Genes Involved in Oral Tumorigenesis.

Parijat Senapati, Aditya Bhattacharya, Sadhan Das, Suchismita Dey, Deepthi Sudarshan, Shyla G, Jyoti Vishwakarma, Surabhi Sudevan, Ravishankar Ramachandran, Tessy Thomas Maliekal and 1 more

Open access · greenAbstract read
In one paragraph

Article in Molecular and cellular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Parijat SenapatiTranscription and Disease Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Researchgrid.419636.f, Jakkur, Bangalore, Karnataka, India.ORCID 0000-0002-7324-1230
Aditya Bhattacharya *Transcription and Disease Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Researchgrid.419636.f, Jakkur, Bangalore, Karnataka, India.
Sadhan Das *Transcription and Disease Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Researchgrid.419636.f, Jakkur, Bangalore, Karnataka, India.ORCID 0000-0002-7153-9519
Suchismita DeyTranscription and Disease Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Researchgrid.419636.f, Jakkur, Bangalore, Karnataka, India.
Deepthi SudarshanTranscription and Disease Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Researchgrid.419636.f, Jakkur, Bangalore, Karnataka, India.
Shyla GCancer Research Program, Rajiv Gandhi Centre for Biotechnologygrid.418917.2, Thiruvananthapuram, Kerala, India.
Jyoti VishwakarmaDivision of Biochemistry and Structural Biology, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.
Surabhi SudevanTranscription and Disease Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Researchgrid.419636.f, Jakkur, Bangalore, Karnataka, India.
Ravishankar RamachandranDivision of Biochemistry and Structural Biology, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.
Tessy Thomas MaliekalCancer Research Program, Rajiv Gandhi Centre for Biotechnologygrid.418917.2, Thiruvananthapuram, Kerala, India.
Tapas K KunduTranscription and Disease Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Researchgrid.419636.f, Jakkur, Bangalore, Karnataka, India.ORCID 0000-0001-7790-214X
Jawaharlal Nehru Centre for Advanced Scientific Research · INCentral Drug Research Institute · INRajiv Gandhi Centre for Biotechnology · IN

Funding

Wellcome Trust
6 · The paper itself

Abstract

Nucleophosmin (NPM1) is a multifunctional histone chaperone that can activate acetylation-dependent transcription from chromatin templates

Indexed as

AnimalsCarcinogenesisCarcinoma, Squamous CellChromatin Assembly and DisassemblyGene Expression RegulationHistone ChaperonesHistonesHumansMouth NeoplasmsNuclear ProteinsNucleophosminPromoter Regions, GeneticHistone ChaperonesHistonesNuclear ProteinsNucleophosminacetylationChIP-seqhistone chaperoneoral cancerprotein-protein interactiontranscription

Identifiers

PMID34898280
PMCPMC8852714
OpenAlexW4220915264

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.