Evidence map›Paper›PMID 34898053›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2022

2D Material-Based Optical Biosensor: Status and Prospect.

Zong-Lin Lei, Bo Guo

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Engineering two-dimensional electronic biosensors.Nature reviews electrical engineering · 2026
    Article
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  11. Optical Bionanosensors for Sepsis Diagnostics.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zong-Lin LeiKey Lab of In-Fiber Integrated Optics of Ministry of Education of China, Harbin Engineering University, Harbin, 150001, China.
Bo GuoKey Lab of In-Fiber Integrated Optics of Ministry of Education of China, Harbin Engineering University, Harbin, 150001, China.ORCID 0000-0002-9728-8885

Funding

111 Project of Harbin Engineering University B13015Heilongjiang Natural Science Foundation JJ2019LH1509National Natural Science Foundation 61875043
6 · The paper itself

Abstract

The combination of 2D materials and optical biosensors has become a hot research topic in recent years. Graphene, transition metal dichalcogenides, black phosphorus, MXenes, and other 2D materials (metal oxides and degenerate semiconductors) have unique optical properties and play a unique role in the detection of different biomolecules. Through the modification of 2D materials, optical biosensor has the advantages that traditional sensors (such as electrical sensing) do not have, and the sensitivity and detection limit are greatly improved. Here, optical biosensors based on different 2D materials are reviewed. First, various detection methods of biomolecules, including surface plasmon resonance (SPR), fluorescence resonance energy transfer (FRET), and evanescent wave and properties, preparation and integration strategies of 2D material, are introduced in detail. Second, various biosensors based on 2D materials are summarized. Furthermore, the applications of these optical biosensors in biological imaging, food safety, pollution prevention/control, and biological medicine are discussed. Finally, the future development of optical biosensors is prospected. It is believed that with their in-depth research in the laboratory, optical biosensors will gradually become commercialized and improve people's quality of life in many aspects.

Indexed as

Biosensing TechniquesFluorescence Resonance Energy TransferGraphiteHumansOxidesPhosphorusSurface Plasmon ResonanceTransition ElementsGraphiteOxidesPhosphorusTransition Elements2D materialsevanescent wavefluorescence resonance energy transferoptical biosensorsurface plasmon resonance

Identifiers

PMID34898053
PMCPMC8811838

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.