Evidence map›Paper›PMID 34898032›Full record

ArticleJournal of the International AIDS Society2021

A one-stop shop model for improved efficiency of pre-exposure prophylaxis delivery in public clinics in western Kenya: a mixed methods implementation science study.

Stephanie D Roche, Josephine Odoyo, Elizabeth Irungu, Benn Kwach, Annabell Dollah, Bernard Nyerere, Sue Peacock, Jennifer F Morton, Gabrielle O'Malley, Elizabeth A Bukusi and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the International AIDS Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Stephanie D RocheDepartment of Global Health, University of Washington, Seattle, Washington, USA.ORCID 0000-0001-7569-3241
Josephine OdoyoCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Elizabeth IrunguPartners in Health and Research Development, Nairobi, Kenya.ORCID 0000-0002-7401-3758
Benn KwachCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Annabell DollahCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Bernard NyerereCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Sue PeacockDepartment of Global Health, University of Washington, Seattle, Washington, USA.
Jennifer F MortonDepartment of Global Health, University of Washington, Seattle, Washington, USA.
Gabrielle O'MalleyDepartment of Global Health, University of Washington, Seattle, Washington, USA.
Elizabeth A BukusiDepartment of Global Health, University of Washington, Seattle, Washington, USA.
Jared M BaetenDepartment of Global Health, University of Washington, Seattle, Washington, USA.ORCID 0000-0001-8242-8438
Kenneth K MugwanyaDepartment of Global Health, University of Washington, Seattle, Washington, USA.
University of Washington · USKenya Medical Research Institute · KEPartners for Health and Development in Africa · KE

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI EDWIN ROBERTO ORELLANA · 1988 to 2026
$104.9M
Optimizing Antiretroviral-Based HIV Prevention for HIV Serodiscordant CouplesR01MH095507 · NIMH · UNIVERSITY OF WASHINGTON · PI BAETEN, JARED · 2011 to 2020
$6.1M
Bill & Melinda Gates Foundation OPP1056051NIAID NIH HHS P30 AI027757NIMH NIH HHS R01 MH095507
6 · The paper itself

Abstract

introductionIn public clinics in Kenya, separate, sequential delivery of the component services of pre-exposure prophylaxis (PrEP) (e.g. HIV testing, counselling, and dispensing) creates long wait times that hinder clients' ability and desire to access and continue PrEP. We conducted a mixed methods study in four public clinics in western Kenya to identify strategies for operationalizing a one-stop shop (OSS) model and evaluate whether this model could improve client wait time and care acceptability among clients and providers without negatively impacting uptake or continuation.

methodsFrom January 2020 through November 2020, we collected and analysed 47 time-and-motion observations using Mann-Whitney U tests, 29 provider and client interviews, 68 technical assistance reports, and clinic flow maps from intervention clinics. We used controlled interrupted time series (cITS) to compare trends in PrEP initiation and on-time returns from a 12-month pre-intervention period (January-December 2019) to an 8-month post-period (January-November 2020, excluding a 3-month COVID-19 wash-out period) at intervention and control clinics.

resultsFrom the pre- to post-period, median client wait time at intervention clinics dropped significantly from 31 to 6 minutes (p = 0.02), while median provider contact time remained around 23 minutes (p = 0.4). Intervention clinics achieved efficiency gains by moving PrEP delivery to lower volume departments, moving steps closer together (e.g. relocating supplies; cross-training and task-shifting), and differentiating clients based on the subset of services needed. Clients and providers found the OSS model highly acceptable and additionally identified increased privacy, reduced stigma, and higher quality client-provider interactions as benefits of the model. From the pre- to post-period, average monthly initiations at intervention and control clinics increased by 6 and 2.3, respectively, and percent of expected follow-up visits occurring on time decreased by 18% and 26%, respectively; cITS analysis of PrEP initiations (n = 1227) and follow-up visits (n = 2696) revealed no significant difference between intervention and control clinics in terms of trends in PrEP initiation and on-time returns (all p>0.05).

conclusionsAn OSS model significantly improved client wait time and care acceptability without negatively impacting initiations or continuations, thus highlighting opportunities to improve the efficiency of PrEP delivery efficiency and client-centredness.

Indexed as

COVID-19HIV InfectionsPre-Exposure ProphylaxisHumansImplementation ScienceKenyaSARS-CoV-2HIV preventionimplementation scienceKenyaorganizational efficiencypre-exposure prophylaxisquality improvement

Identifiers

PMID34898032
PMCPMC8666585
OpenAlexW4200101826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.