Evidence map›Paper›PMID 34897984›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2022

Pediatric heart transplant waiting times in the United States since the 2016 allocation policy change.

Ryan J Williams, Minmin Lu, Lynn A Sleeper, Elizabeth D Blume, Paul Esteso, Francis Fynn-Thompson, Christina J Vanderpluym, Simone Urbach, Kevin P Daly

Open access · greenAbstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Myocardial recovery in children supported with a durable ventricular assist device-a systematic review.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2023
    Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ryan J WilliamsDivision of Pediatric Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.ORCID 0000-0001-8661-9151
Minmin LuDepartment of Cardiology, Boston Children's Hospital, Boston, Massachusetts, USA.
Lynn A SleeperDepartment of Cardiology, Boston Children's Hospital, Boston, Massachusetts, USA.
Elizabeth D BlumeDepartment of Cardiology, Boston Children's Hospital, Boston, Massachusetts, USA.
Paul EstesoDepartment of Cardiology, Boston Children's Hospital, Boston, Massachusetts, USA.
Francis Fynn-ThompsonDepartment of Cardiac Surgery, Boston Children's Hospital, Boston, Massachusetts, USA.
Christina J VanderpluymDepartment of Cardiology, Boston Children's Hospital, Boston, Massachusetts, USA.
Simone UrbachDepartment of Cardiology, Boston Children's Hospital, Boston, Massachusetts, USA.
Kevin P DalyDepartment of Cardiology, Boston Children's Hospital, Boston, Massachusetts, USA.ORCID 0000-0003-4327-1532
Boston Children's Hospital · USUniversity of California, Los Angeles · US

Funding

RESEARCH METHODS IN PEDIATRICS HEART DISEASET32HL007572 · NHLBI · CHILDREN'S HOSPITAL BOSTON · PI Sarah D DE FERRANTI, Jane W. Newburger · 1985 to 2026
$13.0M
NHLBI NIH HHS T32 HL007572
6 · The paper itself

Abstract

We describe waiting times for pediatric heart transplant (HT) candidates after the 2016 revision to the US allocation policy. The OPTN database was queried for pediatric HT candidates listed between 7/2016 and 4/2019. Of the 1789 included candidates, 65% underwent HT, 14% died/deteriorated, 8% were removed for improvement, and 13% were still waiting at the end of follow-up. Most candidates were status 1A at HT (81%). Median wait times differ substantially by listing status, blood type, and recipient weight. The likelihood of HT was lower in candidates <25 kg and in those with blood type O; The <25 kg, blood type O subgroup experiences longer wait times and higher wait list mortality. For status 1A candidates, median wait times were 108 days (≤25 kg, blood type O), 80 days (≤25 kg, non-O), 47 days (>25 kg, O), and 24 days (>25 kg, non-O). We found that centers with more selective organ acceptance practices, based on a lower median Pediatric Heart Donor Assessment Tool (PH-DAT) score for completed transplants, experience longer status 1A wait times for their listed patients. These data can be used to counsel families and to select appropriate advanced heart failure therapies to support patients to transplant.

Indexed as

Heart Defects, CongenitalHeart TransplantationTissue and Organ ProcurementChildHumansPolicyTissue DonorsUnited StatesWaiting Listsorgan allocationOrgan Procurement and Transplantation Network (OPTN)waitlist management

Identifiers

PMID34897984
PMCPMC9234036
OpenAlexW4200005455

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.