Evidence map›Paper›PMID 34897589›Full record

ArticleEuropean journal of hybrid imaging2021

Initial experience in staging primary oesophageal/gastro-oesophageal cancer with 18F-FDG PET/MRI.

Amy R Sharkey, Bert-Ram Sah, Samuel J Withey, Shaheel Bhuva, Radhouene Neji, Sami Jeljeli, Adrian Green, Gary J R Cook, Vicky Goh, Guy’s & St Thomas’ Oesophago-Gastric Research Group

Open access · goldAbstract read
In one paragraph

Article in European journal of hybrid imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. PET/MRI is superior to PET/CT in detecting oesophago and gastric carcinomas: a meta-analysis.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. [European journal of nuclear medicine and molecular imaging · 2023
    Article
  6. Review
  7. State-of-the-art imaging in oesophago-gastric cancer.The British journal of radiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Amy R SharkeyDepartment of Cancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK. amyrose.sharkey@gstt.nhs.uk.ORCID http://orcid.org/0000-0002-0916-9123
Bert-Ram SahDepartment of Diagnostic, Interventional, and Pediatric Radiology, Inselspital, University of Bern, Bern, Switzerland.
Samuel J WitheyDepartment of Cancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Shaheel BhuvaKing's College London and Guy's and St Thomas' PET Centre, St Thomas' Hospital, London, UK.
Radhouene NejiMR Research Collaborations, Siemens Healthcare, Frimley, UK.
Sami JeljeliKing's College London and Guy's and St Thomas' PET Centre, St Thomas' Hospital, London, UK.
Adrian GreenDepartment of Cancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Gary J R CookDepartment of Cancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Vicky GohDepartment of Cancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Guy’s & St Thomas’ Oesophago-Gastric Research Group
St Thomas' Hospital · GBKing's College London · GBSiemens (United Kingdom) · GBUniversity of Bern · CH

Funding

Cancer Research UK 16463Wellcome Trust
6 · The paper itself

Abstract

background

resultsOut of 26 participants, 22 (20 males; mean ± SD age 68.8 ± 8.7 years) completed 18F-FDG PET/CT and PET/MRI. Compared to the tumour board, the primary tumour was staged concordantly in 55% (12/22) with PET/MRI and 36% (8/22) with PET/CT; the nodal stage was concordant in 45% (10/22) with PET/MRI and 50% (11/22) with PET/CT. There was no statistical difference in PET/CT and PET/MRI staging performance (p > 0.05, for T and N staging). The staging of distant metastases was concordant with the tumour board in 95% (21/22) with both PET/MRI and PET/CT. Of participants with distant metastatic disease, PET/MRI detected additional metastases in 30% (3/10).

conclusionIn this preliminary study, compared to 18F-FDG PET/CT, 18F-FDG PET/MRI showed non-significant higher concordance with T-staging, but no difference with N or M-staging. Additional metastases detected by 18F-FDG PET/MRI may be of additive clinical value.

Indexed as

Gastro-oesophageal cancerOesophageal cancerPET/CTPET/MR

Identifiers

PMID34897589
PMCPMC8666393
OpenAlexW4200355643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.