ArticleNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2022
Is Adolescent E-Cigarette Use Associated With Subsequent Smoking? A New Look.
Article in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Electronic cigarettes and subsequent cigarette smoking in young people: A systematic review.Addiction (Abingdon, England) · 2025Pooled it
- A systematic review and meta-analysis of the association between e-cigarette use among non-tobacco users and initiating smoking of combustible cigarettes.Harm reduction journal · 2024Pooled it
- Systematic Review and Critical Analysis of Longitudinal Studies Assessing Effect of E-Cigarettes on Cigarette Initiation among Adolescent Never-Smokers.International journal of environmental research and public health · 2023Pooled it
- Susceptibility to E-Cigarette and Cigarette Use Among U.S. Adolescents.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2026Article
- Perceptions of Health Risks and Accessibility: A Social Media-Based Pilot Study of Factors Influencing Use of Vaping and Combustible Tobacco Products.International journal of environmental research and public health · 2025Article
- Increased e-cigarette use prevalence is associated with decreased smoking prevalence among US adults.Harm reduction journal · 2024Article
- The "Gateway" hypothesis: evaluation of evidence and alternative explanations.Harm reduction journal · 2024Review
- What are the characteristics of disposable electronic cigarettes users in Switzerland? A quantitative study among 14-25 year olds.BMJ public health · 2024Article
- Vaping: Public Health, Social Media, and Toxicity.Online journal of public health informatics · 2024Article
- Vuse Solo e-cigarettes do not provide net benefits to public health: a scientific analysis of FDA's marketing authorisation.Tobacco control · 2024Review
- The interaction of e-cigarette use and mental health symptoms on risk of cigarette smoking initiation among young adults in the United States.Addiction (Abingdon, England) · 2023Article
- Article
- Are the Relevant Risk Factors Being Adequately Captured in Empirical Studies of Smoking Initiation? A Machine Learning Analysis Based on the Population Assessment of Tobacco and Health Study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023Article
- Electronic Cigarettes: A Pro-Con Review of the Current Literature.The journal of allergy and clinical immunology. In practice · 2022Review
- E-Cigarettes, the FDA's Strategic Orientation, and Lessons from the Opioid Crisis.The American journal of bioethics : AJOB · 2022Article
- Use of Electronic Cigarettes Among Cannabis-Naive Adolescents and Its Association With Future Cannabis Use.JAMA network open · 2022Article
- Which Regulatory Framework Is Best for Nicotine Vaping?American journal of public health · 2022Article
- Further investigation of gateway effects using the PATH study.F1000Research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionProspective studies have consistently reported a strong association between e-cigarette use and subsequent cigarette smoking, but many failed to adjust for important risk factors.
methodsUsing longitudinal data from the Population Assessment of Tobacco and Health (PATH) Study, we employed multivariable logistic regressions to assess the adolescent vaping-to-smoking relationship, with four regressions (Models 1-4) sequentially adding more risk factors.Our sample included all waves (waves 1-5) of the PATH Study.
resultsThe association between ever e-cigarette use and subsequent cigarette smoking decreased substantially in magnitude when adding more control variables, including respondents' sociodemographic characteristics, exposure to tobacco users, cigarette susceptibility, and behavioral risk factors. Using the most recent data (waves 4-4.5 and waves 4.5-5), this association was not significant in the most complete model (Model 4). Using wave 4.5-5 data, the adjusted odds ratio (aOR) for ever e-cigarette use at initial wave and subsequent past 12-month smoking declined from 4.07 (95% confidence interval [CI, 2.86-5.81) in Model 1, adjusting only for sociodemographic characteristics, to 1.35 (95% CI, 0.84-2.16) in Model 4, adjusting for all potential risk factors. Similarly, the aOR of ever e-cigarette use and past 30-day smoking at wave 5 decreased from 3.26 (95% CI, 1.81-5.86) in Model 1 to 1.21 (95% CI, 0.59-2.48) with all covariates (Model 4).
conclusionsAmong adolescent never cigarette smokers, those who had ever used e-cigarettes at baseline, compared with never e-cigarette users, exhibited modest or non-significant increases in subsequent past 12-month or past 30-day smoking when adjusting for behavioral risk factors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.