Evidence map›Paper›PMID 34897429›Full record

ArticleG3 (Bethesda, Md.)2022

The genome of the zebra mussel, Dreissena polymorpha: a resource for comparative genomics, invasion genetics, and biocontrol.

Michael A McCartney, Benjamin Auch, Thomas Kono, Sophie Mallez, Ying Zhang, Angelico Obille, Aaron Becker, Juan E Abrahante, John Garbe, Jonathan P Badalamenti and 9 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Rapid turnover of sex-determining architecture in invasive mussels.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The quagga mussel,Frontiers in cell and developmental biology · 2024
    Review
  10. Article
  11. Invasive mussels fashion silk-like byssus via mechanical processing of massive horizontally acquired coiled coils.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
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  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 2 countries.

Michael A McCartneyDepartment of Fisheries, Wildlife and Conservation Biology, Minnesota Aquatic Invasive Species Research Center, University of Minnesota, St. Paul, MN 55108, USA.
Benjamin AuchUniversity of Minnesota Genomics Center, Minneapolis, MN 55455, USA.ORCID 0000-0003-3125-5797
Thomas KonoMinnesota Supercomputing Institute, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0002-1388-3194
Sophie MallezDepartment of Fisheries, Wildlife and Conservation Biology, Minnesota Aquatic Invasive Species Research Center, University of Minnesota, St. Paul, MN 55108, USA.
Ying ZhangMinnesota Supercomputing Institute, University of Minnesota, Minneapolis, MN 55455, USA.
Angelico ObilleInstitute of Biomaterials & Biomedical Engineering, University of Toronto, Toronto, ON M5S 3G9, Canada.ORCID 0000-0002-3721-0840
Aaron BeckerUniversity of Minnesota Genomics Center, Minneapolis, MN 55455, USA.
Juan E AbrahanteUniversity of Minnesota Informatics Institute, Minneapolis, MN 55455, USA.
John GarbeUniversity of Minnesota Genomics Center, Minneapolis, MN 55455, USA.
Jonathan P BadalamentiUniversity of Minnesota Genomics Center, Minneapolis, MN 55455, USA.ORCID 0000-0001-8988-7717
Adam HermanMinnesota Supercomputing Institute, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0001-7463-9462
Hayley MangelsonPhase Genomics, Seattle, WA 98109, USA.
Ivan LiachkoPhase Genomics, Seattle, WA 98109, USA.
Shawn SullivanPhase Genomics, Seattle, WA 98109, USA.
Eli D SoneInstitute of Biomaterials & Biomedical Engineering, University of Toronto, Toronto, ON M5S 3G9, Canada.
Sergey KorenGenome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, Bethesda, MD 20892, USA.
Kevin A T SilversteinMinnesota Supercomputing Institute, University of Minnesota, Minneapolis, MN 55455, USA.
Kenneth B BeckmanUniversity of Minnesota Genomics Center, Minneapolis, MN 55455, USA.
Daryl M GohlUniversity of Minnesota Genomics Center, Minneapolis, MN 55455, USA.ORCID 0000-0002-4434-2788
University of Minnesota · USUniversity of Toronto · CANational Human Genome Research Institute · US

Funding

A method for the culture-free discovery and host affiliation of novel viruses from metagenomic samplesR44AI162570 · NIAID · PHASE GENOMICS, INC. · PI LIACHKO, IVAN · 2021 to 2022
$1.6M
A proximity ligation method to track mobile element hostsR44AI150008 · NIAID · PHASE GENOMICS, INC. · PI LIACHKO, IVAN · 2020 to 2021
$1.5M
NIAID NIH HHS R44 AI150008
6 · The paper itself

Abstract

The zebra mussel, Dreissena polymorpha, continues to spread from its native range in Eurasia to Europe and North America, causing billions of dollars in damage and dramatically altering invaded aquatic ecosystems. Despite these impacts, there are few genomic resources for Dreissena or related bivalves. Although the D. polymorpha genome is highly repetitive, we have used a combination of long-read sequencing and Hi-C-based scaffolding to generate a high-quality chromosome-scale genome assembly. Through comparative analysis and transcriptomics experiments, we have gained insights into processes that likely control the invasive success of zebra mussels, including shell formation, synthesis of byssal threads, and thermal tolerance. We identified multiple intact steamer-like elements, a retrotransposon that has been linked to transmissible cancer in marine clams. We also found that D. polymorpha have an unusual 67 kb mitochondrial genome containing numerous tandem repeats, making it the largest observed in Eumetazoa. Together these findings create a rich resource for invasive species research and control efforts.

Indexed as

DreissenaAnimalsEcosystemGenomeGenomicsIntroduced SpeciesDreissena polymorphagenomeRNA-Seqshell formationstress responsethermal tolerancezebra mussel

Identifiers

PMID34897429
PMCPMC9210306
OpenAlexW4200248721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.