Evidence map›Paper›PMID 34897344›Full record

ArticleLab on a chip2021

Droplet-assisted electrospray phase separation using an integrated silicon microfluidic platform.

Yan Zhang, Sungho Kim, Weihua Shi, Yaoyao Zhao, Insu Park, Christopher Brenden, Hrishikesh Iyer, Prasoon Jha, Rashid Bashir, Jonathan V Sweedler and 1 more

Abstract read
In one paragraph

Article in Lab on a chip, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yan ZhangDepartment of Electrical and Computer Engineering, University of Illinois Urbana Champaign, IL 61801, USA. yvlasov@illinois.edu.
Sungho KimDepartment of Electrical and Computer Engineering, University of Illinois Urbana Champaign, IL 61801, USA. yvlasov@illinois.edu.ORCID 0000-0002-7838-9744
Weihua ShiDepartment of Electrical and Computer Engineering, University of Illinois Urbana Champaign, IL 61801, USA. yvlasov@illinois.edu.
Yaoyao ZhaoDepartment of Chemistry and the Beckman Institute, University of Illinois Urbana Champaign, IL 61801, USA.
Insu ParkDepartment of Bioengineering, University of Illinois Urbana Champaign, IL 61801, USA.
Christopher BrendenDepartment of Bioengineering, University of Illinois Urbana Champaign, IL 61801, USA.ORCID 0000-0003-2261-7434
Hrishikesh IyerDepartment of Electrical and Computer Engineering, University of Illinois Urbana Champaign, IL 61801, USA. yvlasov@illinois.edu.
Prasoon JhaDepartment of Electrical and Computer Engineering, University of Illinois Urbana Champaign, IL 61801, USA. yvlasov@illinois.edu.
Rashid BashirDepartment of Bioengineering, University of Illinois Urbana Champaign, IL 61801, USA.ORCID 0000-0002-7225-9180
Jonathan V SweedlerDepartment of Chemistry and the Beckman Institute, University of Illinois Urbana Champaign, IL 61801, USA.ORCID 0000-0003-3107-9922
Yurii VlasovDepartment of Electrical and Computer Engineering, University of Illinois Urbana Champaign, IL 61801, USA. yvlasov@illinois.edu.ORCID 0000-0002-5864-3346

Funding

MINIMALLY-INVASIVE NANO-DIALYSIS NEURAL PROBE FOR MULTIPLEXED MONITORING OF NEUROCHEMICALS WITH HIGH SPATIO-TEMPORAL RESOLUTIONUF1NS107677 · NINDS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BASHIR, RASHID, SWEEDLER, JONATHAN V. · 2018 to 2018
$3.0M
NINDS NIH HHS UF1 NS107677
6 · The paper itself

Abstract

We report a silicon microfluidic platform that enables monolithic integration of transparent micron-scale microfluidic channels, an on-chip segmentation of analyte flows into picoliter-volume droplets, and a nano-electrospray ionization emitter that enables spatial and temporal separation of oil and aqueous phases during electro-spray for subsequent mass spectrometry analysis.

Indexed as

Microfluidic Analytical TechniquesMicrofluidicsSiliconSpectrometry, Mass, Electrospray IonizationSilicon

Identifiers

PMID34897344
PMCPMC8691365

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.