Evidence map›Paper›PMID 34897158›Full record

ArticleThe Journal of veterinary medical science2022

Diffusion tensor imaging-based quantitative analysis of the spinal cord in Pembroke Welsh Corgis with degenerative myelopathy.

Eiji Naito, Kohei Nakata, Hiroki Sakai, Osamu Yamato, Md Shafiqul Islam, Sadatoshi Maeda, Hiroaki Kamishina

Open access · diamondAbstract read
In one paragraph

Article in The Journal of veterinary medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Eiji NaitoJoint Graduate School of Veterinary Sciences, Gifu University, Gifu 501-1193, Japan.
Kohei NakataThe Animal Medical Center of Gifu University, Faculty of Applied Biological Sciences, Gifu University, Gifu 501-1112, Japan.
Hiroki SakaiJoint Graduate School of Veterinary Sciences, Gifu University, Gifu 501-1193, Japan.
Osamu YamatoJoint Faculty of Veterinary Medicine Kagoshima University, Kagoshima 890-8580, Japan.
Md Shafiqul IslamJoint Faculty of Veterinary Medicine Kagoshima University, Kagoshima 890-8580, Japan.
Sadatoshi MaedaJoint Graduate School of Veterinary Sciences, Gifu University, Gifu 501-1193, Japan.
Hiroaki KamishinaJoint Graduate School of Veterinary Sciences, Gifu University, Gifu 501-1193, Japan.
Gifu University · JPGifu University of Medical Science · JPKagoshima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canine degenerative myelopathy (DM) is a progressive neurodegenerative disease of the spinal cord. The diagnosis is based on the observation of clinical signs, genetic testing, and exclusion of other spinal cord diseases, and a definitive diagnosis of DM can only be confirmed by postmortem histopathological findings. The aim of this study was to investigate the diagnostic ability of diffusion tensor imaging (DTI) for DM. Eight DM-affected Pembroke Welsh Corgis, thirteen dogs with thoracolumbar intervertebral disk herniation (IVDH), and six healthy control dogs were included. All dogs were scanned using a 3.0-T MRI system. Apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values were calculated for each intervertebral disk level slice between T8-T9 and L2-L3 intervertebral disk levels, and the entire area of the thoracolumbar spinal cord between T8-T9 and L2-L3 intervertebral disk levels (T8-L3 region). The ADC and FA values of the T8-L3 region were significantly lower in the DM group than in the IVDH group. The ADC values for the T8-L3 region had a moderate negative correlation with clinical duration (r

Indexed as

Dog DiseasesNeurodegenerative DiseasesSpinal Cord DiseasesAnimalsAnisotropyDiffusion Tensor ImagingDogsSpinal Corddegenerative myelopathydiffusion tensor imagingdogMRIthoracolumbar spinal cord

Identifiers

PMID34897158
PMCPMC8920728
OpenAlexW4200192488

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.