Evidence map›Paper›PMID 34897031›Full record

ArticleAging2021

hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 aggravate glioma via miR-338-5p/IKBIP.

Jian Liang, Xing Li, Jian Xu, Guang-Mou Cai, Jian-Xuan Cao, Bo Zhang

Open access · hybridAbstract read
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Circular RNAeLife · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jian LiangThe Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen, China.
Xing LiSchool of Medicine, Southern University of Science and Technology, Shenzhen, China.
Jian XuDepartment of Hematology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen, China.
Guang-Mou CaiThe Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen, China.
Jian-Xuan CaoThe Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen, China.
Bo ZhangThe Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen, China.
Jinan University · CNSouthern University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioma is a primary intracranial tumor with high morbidity and mortality. We acquired miR-338-5p, which suppresses the development of glioma, from the GEO and CGGA databases. In addition, we predicted that hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 could relieve the silencing of IKBIP by miR-338-5p. By analyzing genes related to IKBIP expression, possible pathways affecting glioma were identified. This study provides new ideas for investigating multiple circRNAs in ceRNAs.

Indexed as

Blotting, WesternBrain NeoplasmsCell Line, TumorGliomaHumansMicroRNAsRNA, CircularSignal TransductionMicroRNAsMIRN338 microRNA, humanRNA, CircularceRNAcircRNAgliomaIKBIPmiR-338-5p

Identifiers

PMID34897031
PMCPMC8714164
OpenAlexW4200240854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.