Evidence map›Paper›PMID 34897030›Full record

ArticleAging2021

Functional rare variant in a

Pengyun Wang, Yifan Wang, Huixin Peng, Jingjing Wang, Qian Zheng, Pengxia Wang, Jing Wang, Hongfu Zhang, Yufeng Huang, Liang Xiong and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

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  5. Effects ofCell cycle (Georgetown, Tex.) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Pengyun WangDepartment of Clinical Laboratory, Liyuan Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, PR China.
Yifan WangHuman Genome Research Center, Cardio-X Institute, College of Life Science and Technology of Huazhong University of Science and Technology, Wuhan, PR China.
Huixin PengHuman Genome Research Center, Cardio-X Institute, College of Life Science and Technology of Huazhong University of Science and Technology, Wuhan, PR China.
Jingjing WangState Key Laboratory for Molecular and Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, PR China.
Qian ZhengHuman Genome Research Center, Cardio-X Institute, College of Life Science and Technology of Huazhong University of Science and Technology, Wuhan, PR China.
Pengxia WangHuman Genome Research Center, Cardio-X Institute, College of Life Science and Technology of Huazhong University of Science and Technology, Wuhan, PR China.
Jing WangHuman Genome Research Center, Cardio-X Institute, College of Life Science and Technology of Huazhong University of Science and Technology, Wuhan, PR China.
Hongfu ZhangHuman Genome Research Center, Cardio-X Institute, College of Life Science and Technology of Huazhong University of Science and Technology, Wuhan, PR China.
Yufeng HuangPrecision Medical Laboratory, Tongji Medical College, Wuhan Children's Hospital (Wuhan Maternal and Child Health Care Hospital), Huazhong University of Science and Technology, Wuhan, PR China.
Liang XiongDepartment of Clinical Laboratory, Liyuan Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, PR China.
Rongfeng ZhangDepartment of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, PR China.
Yunlong XiaDepartment of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, PR China.
Qing K WangHuman Genome Research Center, Cardio-X Institute, College of Life Science and Technology of Huazhong University of Science and Technology, Wuhan, PR China.
Chengqi XuHuman Genome Research Center, Cardio-X Institute, College of Life Science and Technology of Huazhong University of Science and Technology, Wuhan, PR China.
Huazhong University of Science and Technology · CNChinese Academy of Sciences · CNDalian Medical University · CNFirst Affiliated Hospital of Dalian Medical University · CNInstitute of Genetics and Developmental Biology · CNWuhan Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objective

methodsWe genotyped rs34166160 in

resultsAllele rs34166160 significantly confers risk to CAD in the GeneID Hubei population which contained 1,440 CAD cases and 2,660 CAD-free controls (observed

conclusionsOur study demonstrates that the functional rare variant rs34166160 in

Indexed as

AllelesBinding SitesCase-Control StudiesCCAAT-Enhancer-Binding ProteinsCell Adhesion Molecules, NeuronalCoronary Artery DiseaseFemaleGenetic Association StudiesGenetic Predisposition to DiseaseHumansMaleMiddle AgedPolymorphism, Single NucleotideReal-Time Polymerase Chain ReactionRisk FactorsCCAAT-Enhancer-Binding ProteinsCell Adhesion Molecules, NeuronalNINJ2 protein, humanC/EBP betacoronary artery diseasegeneticsNINJ2SNP

Identifiers

PMID34897030
PMCPMC8714150
OpenAlexW4200608079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.