Evidence map›Paper›PMID 34896666›Full record

ArticleDiagnostic microbiology and infectious disease2022

Duration of SARS-CoV-2 viremia and its correlation to mortality and inflammatory parameters in patients hospitalized for COVID-19: a cohort study.

Karl Hagman, Magnus Hedenstierna, Johan Rudling, Patrik Gille-Johnson, Berit Hammas, Malin Grabbe, Jan Jakobsson, Joakim Dillner, Johan Ursing

Open access · hybridAbstract read
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 42 citations in OpenAlex.

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  13. The kinetics of SARS-CoV-2 viremia in COVID-19 patients receiving remdesivir.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Karl HagmanDepartment of Infectious Diseases, Danderyd Hospital, Stockholm, Sweden; Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden. Electronic address: karl.hagman@ki.se.
Magnus HedenstiernaDepartment of Infectious Diseases, Danderyd Hospital, Stockholm, Sweden.
Johan RudlingDepartment of Infectious Diseases, Danderyd Hospital, Stockholm, Sweden.
Patrik Gille-JohnsonDepartment of Infectious Diseases, Danderyd Hospital, Stockholm, Sweden.
Berit HammasDepartment of Microbiology, Karolinska University Hospital, Stockholm Sweden.
Malin GrabbeDepartment of Microbiology, Karolinska University Hospital, Stockholm Sweden.
Jan JakobssonDepartment of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden; Department of Anesthesia and Intensive Care, Danderyd Hospital, Stockholm, Sweden.
Joakim DillnerKarolinska University Laboratory, Stockholm, Sweden.
Johan UrsingDepartment of Infectious Diseases, Danderyd Hospital, Stockholm, Sweden; Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.
Danderyds sjukhus · SEKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 viremia at admission is associated with high risk for mortality. However, longitudinal data on viremia duration are limited. Viremic patients hospitalized for COVID-19 were included in a cohort. Time to serum viral clearance and the effect of viremia duration on the odds of mortality were calculated. One hundred and twenty-one viremic patients were included. Median age was 62 (IQR 52-71) years and 68% were males. The total in-hospital mortality of the cohort was 33%. Median time from admission to serum viral clearance was 7 (95% CI 6-8) days. Duration of viremia showed a relative risk ratio of 1.40 (95% CI 1.02-1.92) for the odds of mortality in an adjusted multinomial logistic regression. Serum viral clearance coincided with defervescence and decreasing C-reactive protein. Median time to serum viral clearance was 7 days after admission. The odds of mortality increased with 40% for each additional day of viremia.

Indexed as

COVID-19SARS-CoV-2Cohort StudiesHospitalizationHumansMaleMiddle AgedViremiaCOVID-19mortalityRNAemiaSARS-CoV-2viremia

Identifiers

PMID34896666
PMCPMC8595972
OpenAlexW3213343112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.