Evidence map›Paper›PMID 34896289›Full record

ArticleNeuroImage2022

Inside information: Systematic within-node functional connectivity changes observed across tasks or groups.

Wenjing Luo, R Todd Constable

Abstract read
In one paragraph

Article in NeuroImage, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Geometric influences on the regional organization of the mammalian brain.bioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Brain fingerprints along the language hierarchy.Frontiers in human neuroscience · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Wenjing LuoDepartment of Biomedical Engineering, Yale University School of Medicine USA.
R Todd ConstableDepartment of Biomedical Engineering, Yale University School of Medicine USA; Radiology and Biomedical Imaging, Yale University School of Medicine USA; Interdepartmental Neuroscience Program, Yale University School of Medicine USA. Electronic address: todd.constable@yale.edu.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
An Individualized, Multidimensional Dimensional Approach to PsychopathologyR01MH121095 · NIMH · YALE UNIVERSITY · PI CONSTABLE, R TODD, SCHEINOST, DUSTIN · 2019 to 2023
$4.2M
NCATS NIH HHS UL1 TR001863NIMH NIH HHS R01 MH121095
6 · The paper itself

Abstract

Mapping the human connectome and understanding its relationship to brain function holds tremendous clinical potential. The connectome has two fundamental components: the nodes and the sconnections between them. While much attention has been given to deriving atlases and measuring the connections between nodes, there have been no studies examining the networks within nodes. Here we demonstrate that each node contains significant connectivity information, that varies systematically across task-induced states and subjects, such that measures based on these variations can be used to classify tasks and identify subjects. The results are not specific for any particular atlas but hold across different atlas resolutions. To date, studies examining changes in connectivity have focused on edge changes and assumed there is no useful information within nodes. Our findings illustrate that for typical atlases, within-node changes can be significant and may account for a substantial fraction of the variance currently attributed to edge changes .

Indexed as

AdultBrainConnectomeFemaleHumansMagnetic Resonance ImagingMaleNerve NetRestYoung Adult

Identifiers

PMID34896289
PMCPMC8840325

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.