Evidence map›Paper›PMID 34895512›Full record

ReviewThe Lancet. Child & adolescent health2022

Extracorporeal membrane oxygenation in children receiving haematopoietic cell transplantation and immune effector cell therapy: an international and multidisciplinary consensus statement.

Matteo Di Nardo, Ali H Ahmad, Pietro Merli, Matthew S Zinter, Leslie E Lehman, Courtney M Rowan, Marie E Steiner, Sangeeta Hingorani, Joseph R Angelo, Hisham Abdel-Azim and 34 more

Abstract readReviewConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Review in The Lancet. Child & adolescent health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

44 authors.

Matteo Di NardoPediatric Intensive Care Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy. Electronic address: matteo.dinardo@opbg.net.
Ali H AhmadDepartment of Pediatrics, Pediatric Critical Care, Houston, TX, USA.
Pietro MerliDepartment of Hematology/Oncology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Matthew S ZinterDepartment of Pediatrics, Divisions of Critical Care and Bone Marrow Transplantation, University of California, San Francisco, CA, USA.
Leslie E LehmanPediatric Hematology-Oncology, Dana-Farber Cancer Institute, Harvard University, Boston, MA, USA.
Courtney M RowanDepartment of Pediatrics, Division of Critical Care, Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN, USA.
Marie E SteinerDepartment of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
Sangeeta HingoraniDepartment of Pediatrics, Division of Nephrology, University of Washington School of Medicine, and the Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Joseph R AngeloRenal Section, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA.
Hisham Abdel-AzimDepartment of Pediatrics, Transplantation and Cell Therapy Program, Keck School of Medicine, University of Southern California, Children's Hospital Los Angeles, Los Angeles, CA, USA.
Sajad J KhazalDepartment of Pediatrics, Stem Cell Transplantation and Cellular Therapy, Houston, TX, USA; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Basirat ShoberuDepartment of Pediatrics, Stem Cell Transplantation and Cellular Therapy, Houston, TX, USA; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Jennifer McArthurDivision of Critical Care Medicine, Department of Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN, USA.
Rajinder BajwaDepartment of Pediatrics, Division of Blood and Marrow Transplantation, Nationwide Children's Hospital, The Ohio State University, Columbus, OH, USA.
Saad GhafoorDivision of Critical Care Medicine, Department of Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN, USA.
Samir H ShahDivision of Pediatric Critical Care Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Hitesh SandhuDivision of Pediatric Critical Care Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Karen MoodyCARTOX Program, and Department of Pediatrics, Supportive Care, Houston, TX, USA.
Brandon D BrownDepartment of Pediatrics, Stem Cell Transplantation and Cellular Therapy, Houston, TX, USA; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Maria E MirelesDepartment of Pharmacy, Houston, TX, USA.
Diana SteppanDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Taylor OlsonDivision of Critical Care Medicine, Children's National Hospital, Washington, DC, USA.
Lakshmi RamanDepartment of Pediatrics, UT Southwestern Medical Center, Dallas, TX, USA.
Brian BridgesDivision of Pediatric Critical Care, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA.
Christine N DuncanPediatric Hematology-Oncology, Dana-Farber Cancer Institute, Harvard University, Boston, MA, USA.
Sung Won ChoiUniversity of Michigan, Rogel Cancer Center, Ann Arbor, MI, USA; Department of Pediatrics, Ann Arbor, MI, USA.
Rita SwinfordDepartment of Pediatrics, Division of Pediatric Nephrology, McGovern Medical School, The University of Texas Health Science Center, Houston, TX, USA.
Matt PadenPediatric Critical Care, Children's Healthcare of Atlanta, and Emory University School of Medicine, Atlanta, GA, USA.
James D FortenberryPediatric Critical Care, Children's Healthcare of Atlanta, and Emory University School of Medicine, Atlanta, GA, USA.
Giles PeekCongenital Heart Center, University of Florida, Gainesville, FL, USA.
Pierre TissieresDivision of Pediatric Intensive Care and Neonatal Medicine, Paris South University Hospital, Le Kremlin-Bicetre, France; Institute of Integrative Biology of the Cell, CNRS, CEA, Univ. Paris Sud, Paris Saclay University, Paris, France.
Daniele De LucaDivision of Pediatrics, Transportation and Neonatal Critical Care Medicine, APHP, Paris Saclay University Hospital, "A.Beclere" Medical Center and Physiopathology and Therapeutic Innovation Unit-INSERM-U999, Paris Saclay University, Paris, France.
Franco LocatelliDepartment of Hematology/Oncology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Selim CorbaciogluDepartment of Pediatric Hematology, Oncology and Stem Cell Transplantation, University of Regensburg, Regensburg, Germany.
Martin KneyberDivision of Pediatric Critical Care Medicine, Department of Pediatrics, Beatrix Children's Hospital Groningen, Groningen, Netherlands; Critical Care, Anesthesiology, Peri-Operative and Emergency Medicine (CAPE), University Medical Centre Groningen, University of Groningen, Groningen, Netherlands.
Alessio FranceschiniDepartment of Cardiosurgery, Cardiology, Heart and Lung Transplant, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Simon NadelPediatric Intensive Care Unit, Imperial College Healthcare NHS Trust, London, UK.
Matthias KumpfInterdisciplinary Pediatric Intensive Care Unit, Universitäetsklinikum Tuebingen, Tuebingen, Germany.
Alessandra LoretiMedical Library, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Roelie Wösten-Van AsperenDepartment of Pediatric Intensive Care, University Medical Center Utrecht/Wilhelmina Children's Hospital, Utrecht, Netherlands.
Orsola GawronskiProfessional Development, Continuing Education and Research Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Joe BrierleyDepartment of Pediatric Intensive Care, Great Ormond Street Hospital for Children, London, UK.
Graeme MacLarenDirector of Cardiothoracic ICU, National University Health System, Singapore, Singapore; Pediatric Intensive Care Unit, The Royal Children's Hospital, Melbourne, Australia.
Kris M MahadeoDepartment of Pediatrics, Stem Cell Transplantation and Cellular Therapy, Houston, TX, USA; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Funding

Prognostic biomarkers for respiratory failure post hematopoietic cell transplantationK23HL150244 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI ROWAN, COURTNEY · 2020 to 2024
$899k
NHLBI NIH HHS K23 HL150244
6 · The paper itself

Abstract

Use of extracorporeal membrane oxygenation (ECMO) in children receiving haematopoietic cell transplantation (HCT) and immune effector cell therapy is controversial and evidence-based guidelines have not been established. Remarkable advancements in HCT and immune effector cell therapies have changed expectations around reversibility of organ dysfunction and survival for affected patients. Herein, members of the Extracorporeal Life Support Organization (ELSO), Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network (HCT and cancer immunotherapy subgroup), the Pediatric Diseases Working Party of the European Society for Blood and Marrow Transplantation (EBMT), the supportive care committee of the Pediatric Transplantation and Cellular Therapy Consortium (PTCTC), and the Pediatric Intensive Care Oncology Kids in Europe Research (POKER) group of the European Society of Pediatric and Neonatal Intensive Care (ESPNIC) provide consensus recommendations on the use of ECMO in children receiving HCT and immune effector cell therapy. These are the first international, multidisciplinary consensus-based recommendations on the use of ECMO in this patient population. This Review provides a clinical decision support tool for paediatric haematologists, oncologists, and critical care physicians during the difficult decision-making process of ECMO candidacy and management. These recommendations can represent a base for future research studies focused on ECMO selection criteria and bedside management.

Indexed as

Extracorporeal Membrane OxygenationHematopoietic Stem Cell TransplantationImmunotherapyPatient SelectionPractice Guidelines as TopicClinical Decision-MakingConsensusHumansPediatricsSocieties, Medical

Identifiers

PMID34895512
PMCPMC9372796

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.