Evidence map›Paper›PMID 34895330›Full record

ArticleJournal of cheminformatics2021

Processing binding data using an open-source workflow.

Errol L G Samuel, Secondra L Holmes, Damian W Young

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cheminformatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. The long road of drug development for endometriosis - Pains, gains, and hopes.Journal of controlled release : official journal of the Controlled Release Society · 2024
    Review
  3. Article
  4. SARS-CoV2 Nsp1 is a metal-dependent DNA and RNA endonuclease.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Article
  5. Fluorescence-Based Protein Stability Monitoring-A Review.International journal of molecular sciences · 2024
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Errol L G SamuelCenter for Drug Discovery, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA. errol.samuel@bcm.edu.ORCID http://orcid.org/0000-0003-4381-9203
Secondra L HolmesCenter for Drug Discovery, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA.
Damian W YoungCenter for Drug Discovery, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA. damian.young@bcm.edu.

Funding

Neutron encoded activity based probesR01GM139295 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI YOUNG, DAMIAN WINSTON, YOUNG, NICOLAS L · 2020 to 2024
$2.2M
Exploring the limits of luciferase multiplexing to assay multiple cellular signaling pathways at onceR01GM138781 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI VENKEN, KOEN JOZEF THEO · 2020 to 2023
$1.6M
NIGMS NIH HHS R01 GM138781NIGMS NIH HHS R01GM138781NIGMS NIH HHS R01 GM139295NIGMS NIH HHS R01GM139295
6 · The paper itself

Abstract

The thermal shift assay (TSA)-also known as differential scanning fluorimetry (DSF), thermofluor, and T

Indexed as

Data analysisData processingDifferential scanning fluorimetryEducationFlow-based programmingFragment-based drug discoveryFragment-based ligand discoveryKNIMEThermal shift assayWorkflows

Identifiers

PMID34895330
PMCPMC8666039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.