Evidence map›Paper›PMID 34895269›Full record

ArticleDiagnostic pathology2021

A minute primary gastric synovial sarcoma with ulcer: a case report.

Kanako Yoshiyasu, Hiroshi Kono, Yudai Hojo, Yoshinori Ishida, Akio Tamura, Keisuke Nakai, Tadayuki Oshima, Hiroto Miwa, Hisashi Shinohara, Seiichi Hirota

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostic pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kanako YoshiyasuDepartment of Surgical Pathology, Hyogo College of Medicine, 1-1 Mukogawacho, 663-8501, Nishinomiya, Hyogo, Japan.
Hiroshi KonoDepartment of Surgical Pathology, Hyogo College of Medicine, 1-1 Mukogawacho, 663-8501, Nishinomiya, Hyogo, Japan.
Yudai HojoUpper Gastrointestinal Division, Department of Surgery, Hyogo College of Medicine, 1-1 Mukogawacho, 663-8501, Nishinomiya, Hyogo, Japan.
Yoshinori IshidaUpper Gastrointestinal Division, Department of Surgery, Hyogo College of Medicine, 1-1 Mukogawacho, 663-8501, Nishinomiya, Hyogo, Japan.
Akio TamuraDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawacho, 663-8501, Nishinomiya, Hyogo, Japan.
Keisuke NakaiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawacho, 663-8501, Nishinomiya, Hyogo, Japan.
Tadayuki OshimaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawacho, 663-8501, Nishinomiya, Hyogo, Japan.
Hiroto MiwaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawacho, 663-8501, Nishinomiya, Hyogo, Japan.
Hisashi ShinoharaUpper Gastrointestinal Division, Department of Surgery, Hyogo College of Medicine, 1-1 Mukogawacho, 663-8501, Nishinomiya, Hyogo, Japan.
Seiichi HirotaDepartment of Surgical Pathology, Hyogo College of Medicine, 1-1 Mukogawacho, 663-8501, Nishinomiya, Hyogo, Japan. hiros@hyo-med.ac.jp.
Hyogo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSynovial sarcomas are a rare type of high-grade sarcomas with unknown cell origin. They arise predominantly in the soft tissues but rarely in the stomach. We recently encountered a rare case of minute gastric synovial sarcoma. CASE PRESENTATION: A 61-year-old Japanese woman was pointed out edematous erosion at the body of the stomach. Biopsy specimen showed dense proliferation of spindle-shaped tumor cells mixed with smooth muscle fibers of the muscularis mucosae. Although the definite histological diagnosis was undetermined, the patient underwent laparoscopic wedge resection of the stomach. Histological examination of the resected sample revealed that the maximum diameter of the tumor was only 6 mm and that dense proliferation of rather uniform spindle tumor cells were observed mainly in the submucosa. Immunohistochemistry showed that they were positive for pan-keratin, CD99 and TLE1. SS18-SSX fusion-specific antibody gave diffuse positive staining to the tumor cells, and analysis using mRNA extracted from paraffin sections revealed that the tumor had SS18-SSX1 fusion gene. Thus, it was diagnosed as gastric synovial sarcoma, monophasic fibrous type.

conclusionsPrimary synovial sarcoma of the stomach is rare and only 47 cases have been reported in the English literature to date. The maximum diameter of the lesion of our case was 6 mm which is the smallest among them.

Indexed as

Biomarkers, TumorFemaleGastrectomyGene FusionHumansLaparoscopyMiddle AgedOncogene Proteins, FusionSarcoma, SynovialStomach NeoplasmsStomach UlcerTreatment OutcomeTumor BurdenBiomarkers, TumorOncogene Proteins, FusionSYT-SSX fusion proteinFusion gene analysisMonophasic fibrous typeSS18-SSX1StomachSynovial sarcoma

Identifiers

PMID34895269
PMCPMC8667358
OpenAlexW4200476063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.