ArticleJournal of nanobiotechnology2021
A thermoreversible antibacterial zeolite-based nanoparticles loaded hydrogel promotes diabetic wound healing via detrimental factor neutralization and ROS scavenging.
Article in Journal of nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Study on the repair effect of photothermal hydrogel with controllable adhesiveness regulated by melanin and magnesium ions on diabetic wounds.Bioactive materials · 2026Article
- Unveiling the potential of inorganic nanoparticle-based scaffolds in wound healing: advances in antimicrobial and regenerative strategies.Nanoscale advances · 2026Review
- An Overview of Zeolites: From Historical Background to Diverse Applications.Molecules (Basel, Switzerland) · 2025Review
- Biocompatible nanostructured chitosan scaffolds for enhanced diabetic wound healing: Innovations and strategies.3 Biotech · 2025Review
- Mechanism and Application of Biomaterials Targeting Reactive Oxygen Species and Macrophages in Inflammation.International journal of molecular sciences · 2024Review
- Application of NaP1 Zeolite Modified with Silanes in Bitumen Foaming Process.Materials (Basel, Switzerland) · 2024Article
- Review
- Current and promising applications of MOF composites in the healing of diabetes wounds.RSC medicinal chemistry · 2024Review
- Construction of programmed time-released multifunctional hydrogel with antibacterial and anti-inflammatory properties for impaired wound healing.Journal of nanobiotechnology · 2024Article
- A Multifunctional Nanozyme Integrating Antioxidant, Antimicrobial and Pro-Vascularity for Skin Wound Management.International journal of nanomedicine · 2024Article
- Marine biomaterials in biomedical nano/micro-systems.Journal of nanobiotechnology · 2023Review
- Wound healing strategies based on nanoparticles incorporated in hydrogel wound patches.RSC advances · 2023Review
- Natural and Synthetic Clay Minerals in the Pharmaceutical and Biomedical Fields.Pharmaceutics · 2023Review
- Advanced polymer hydrogels that promote diabetic ulcer healing: mechanisms, classifications, and medical applications.Biomaterials research · 2023Review
- Construction of Smart Biomaterials for Promoting Diabetic Wound Healing.Molecules (Basel, Switzerland) · 2023Review
- Mussel-inspired collagen-hyaluronic acid composite scaffold with excellent antioxidant properties and sustained release of a growth factor for enhancing diabetic wound healing.Materials today. Bio · 2022Article
- Glucose/ROS cascade-responsive ceria nanozymes for diabetic wound healing.Materials today. Bio · 2022Article
- Advances in Delivering Oxidative Modulators for Disease Therapy.Research (Washington, D.C.) · 2022Review
- Advances in hydrogels for capturing and neutralizing inflammatory cytokines.Journal of tissue engineeringReview
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundAs recovery time of diabetic wound injury is prolonged by the production of detrimental factors, including reactive oxygen species (ROS) and inflammatory cytokines, attenuating the oxidative stress and inflammatory reactions in the microenvironment of the diabetic wound site would be significant. EXPERIMENTAL
designIn our study, we prepared thermoreversible, antibacterial zeolite-based nanoparticles loaded hydrogel to promote diabetic wound healing via the neutralization of detrimental factors such as inflammatory cytokines and ROS.
resultsThe cerium (Ce)-doped biotype Linde type A (LTA) zeolite nanoparticles synergistically eliminated mitochondrial ROS and neutralized free inflammatory factors, thus remodeling the anti-inflammatory microenvironment of the wound and enhancing angiogenesis. Moreover, the thermoreversible hydrogel composed of Pluronic F127 and chitosan demonstrated strong haemostatic and bactericidal behavior.
conclusionsIn conclusion, the obtained thermoreversible, antibacterial, zeolite-based nanoparticles loaded hydrogels represent a multi-targeted combination therapy for diabetic wound healing.
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