SynthesisThe international journal of behavioral nutrition and physical activity2021
A systematic review of artificial intelligence chatbots for promoting physical activity, healthy diet, and weight loss.
Synthesis in The international journal of behavioral nutrition and physical activity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers, 10 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
109 citing papers in PubMed, 10 syntheses or guidelines pooled it, 248 citations in OpenAlex.
- Meta-analysis of smartphone applications targeting eating behaviour for weight loss.Scientific reports · 2026Pooled it
- Conversational agent-based interventions for lifestyle behavior modification in older adults: a systematic review.Systematic reviews · 2025Pooled it
- Effectiveness of Communication Competence in AI Conversational Agents for Health: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Pooled it
- The Effectiveness and Feasibility of Conversational Agents in Supporting Care for Patients With Cancer: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Natural Language Processing Chatbot-Based Interventions for Improvement of Diet, Physical Activity, and Tobacco Smoking Behaviors: Systematic Review.JMIR mHealth and uHealth · 2025Pooled it
- Chatbot Artificial Intelligence for Genetic Cancer Risk Assessment and Counseling: A Systematic Review and Meta-Analysis.JCO clinical cancer informatics · 2023Pooled it
- Effectiveness and Acceptability of Conversational Agents for Smoking Cessation: A Systematic Review and Meta-analysis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023Pooled it
- Conversational Agents for Body Weight Management: Systematic Review.Journal of medical Internet research · 2023Pooled it
- Artificial Intelligence-Based Chatbots for Promoting Health Behavioral Changes: Systematic Review.Journal of medical Internet research · 2023Pooled it
- Perceptions of Patients and Health Professionals Regarding the Experience of Patients With a Hybrid Cardiac Rehabilitation Program.Research in nursing & health · 2026Article
- Evaluation of the applicability of AI chatbots in addressing health management issues for living kidney donors.International urology and nephrology · 2026Article
- Artificial Intelligence Interventions Targeting Obesity-Related Behaviors: Protocol for a Scoping Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Article
- User needs and design opportunities for a conversational agent for tuberculosis treatment: A mixed-methods study.PLOS digital health · 2026Article
- Artificial Intelligence as a Personal Coach: A Narrative Review of Benefits and Risks in Educational and Health Contexts.Behavioral sciences (Basel, Switzerland) · 2026Review
- Short-Term Efficacy of the Artificial Intelligence HeartBot II in Increasing Awareness and Knowledge of Heart Attack in Women: Protocol for a Randomized Controlled Trial With a Waitlist Control.JMIR research protocols · 2026Article
- Shaping the Future of Men's Health: How AI Could Be a Transformative Tool for Better Patient Outcomes and Provider Efficiency.Journal of medical Internet research · 2026Article
- Evaluation of the Feasibility and Acceptability of Perfect Fit, a Virtual Coach-Based mHealth Intervention for Smoking Cessation and Physical Activity in Adults: Mixed Methods Study.JMIR human factors · 2026Article
- Toward tailored implementation of an artificial intelligence-based healthy dietary chatbot: differences in technology acceptance pathways by health consciousness and user characteristics.BMC medical informatics and decision making · 2026Article
- A Bilingual AI-Based Chatbot for Nutrition Education in a Food Is Medicine Intervention for High-Risk Pregnant Women: Design and Development Study.JMIR formative research · 2026Article
49 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThis systematic review aimed to evaluate AI chatbot characteristics, functions, and core conversational capacities and investigate whether AI chatbot interventions were effective in changing physical activity, healthy eating, weight management behaviors, and other related health outcomes.
methodsIn collaboration with a medical librarian, six electronic bibliographic databases (PubMed, EMBASE, ACM Digital Library, Web of Science, PsycINFO, and IEEE) were searched to identify relevant studies. Only randomized controlled trials or quasi-experimental studies were included. Studies were screened by two independent reviewers, and any discrepancy was resolved by a third reviewer. The National Institutes of Health quality assessment tools were used to assess risk of bias in individual studies. We applied the AI Chatbot Behavior Change Model to characterize components of chatbot interventions, including chatbot characteristics, persuasive and relational capacity, and evaluation of outcomes.
resultsThe database search retrieved 1692 citations, and 9 studies met the inclusion criteria. Of the 9 studies, 4 were randomized controlled trials and 5 were quasi-experimental studies. Five out of the seven studies suggest chatbot interventions are promising strategies in increasing physical activity. In contrast, the number of studies focusing on changing diet and weight status was limited. Outcome assessments, however, were reported inconsistently across the studies. Eighty-nine and thirty-three percent of the studies specified a name and gender (i.e., woman) of the chatbot, respectively. Over half (56%) of the studies used a constrained chatbot (i.e., rule-based), while the remaining studies used unconstrained chatbots that resemble human-to-human communication.
conclusionChatbots may improve physical activity, but we were not able to make definitive conclusions regarding the efficacy of chatbot interventions on physical activity, diet, and weight management/loss. Application of AI chatbots is an emerging field of research in lifestyle modification programs and is expected to grow exponentially. Thus, standardization of designing and reporting chatbot interventions is warranted in the near future. SYSTEMATIC REVIEW REGISTRATION: International Prospective Register of Systematic Reviews (PROSPERO): CRD42020216761 .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.