Evidence map›Paper›PMID 34895162›Full record

ArticleBMC nephrology2021

Mesangial sclerosis in a patient with type 1 diabetes following simultaneous pancreas-kidney transplantation despite maintenance of normoglycemia: a case report.

Boonphiphop Boonpheng, Jonathan E Zuckerman, Gerald S Lipshutz, Gabriel M Danovitch, Angela Phelps, Michele Pena, Julie M Yabu

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Boonphiphop BoonphengDepartment of Medicine, Division of Nephrology, David Geffen UCLA School of Medicine, 7-155 Factor Building; Mail Code 168917, Los Angeles, CA, 90095, USA.
Jonathan E ZuckermanDepartment of Pathology and Laboratory Medicine, David Geffen UCLA School of Medicine, Los Angeles, USA.
Gerald S LipshutzDepartment of Surgery, Division of Liver and Pancreas Transplantation, David Geffen UCLA School of Medicine, Los Angeles, USA.
Gabriel M DanovitchDepartment of Medicine, Division of Nephrology, David Geffen UCLA School of Medicine, 7-155 Factor Building; Mail Code 168917, Los Angeles, CA, 90095, USA.
Angela PhelpsDepartment of Urology, David Geffen UCLA School of Medicine, Los Angeles, USA.
Michele PenaDepartment of Urology, David Geffen UCLA School of Medicine, Los Angeles, USA.
Julie M YabuDepartment of Medicine, Division of Nephrology, David Geffen UCLA School of Medicine, 7-155 Factor Building; Mail Code 168917, Los Angeles, CA, 90095, USA. jyabu@mednet.ucla.edu.ORCID 0000-0002-2819-4674
University of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSimultaneous pancreas-kidney transplantation is considered a curative treatment for type 1 diabetes complicated by end-stage kidney disease. We report herein a case of mesangial sclerosis in a patient who underwent successful kidney-pancreas transplantation despite well-controlled glucose and excellent pancreatic allograft function. CASE PRESENTATION: A 76-year-old type 1 diabetic man who underwent a simultaneous pancreas-kidney transplantation 19 years prior presented with persistent nephrotic range proteinuria although creatinine was at his baseline (normal) level. Hemoglobin A1c and fasting glucose were well controlled without the use of insulin or oral antihyperglycemic agents. Serum lipase and amylase were within the reference range and there was no evidence of donor-specific antibodies. Kidney allograft biopsy was performed to evaluate proteinuria and showed diffuse capillary loop thickening and diffuse moderate to severe mesangial sclerosis resembling diabetic nephropathy.

conclusionsThis case demonstrates a case of mesangial sclerosis resembling diabetic nephropathy in a patient with good glucose control after simultaneous pancreas-kidney transplantation with excellent pancreatic allograft function.

Indexed as

Kidney TransplantationPancreas TransplantationAgedBlood GlucoseDiabetes Mellitus, Type 1Diabetic NephropathiesHumansMaleNephrotic SyndromePostoperative ComplicationsReference ValuesSclerosisBlood GlucoseCase reportDiabetic nephropathyKidney-pancreas transplantMesangial sclerosis

Identifiers

PMID34895162
PMCPMC8666029
OpenAlexW4200321474

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.