Evidence map›Paper›PMID 34895156›Full record

ReviewBMC nephrology2021

A case of Podocytic Infolding Glomerulopathy with SLE and literature review.

Xi Liu, Jieli Huang, Kun Zhang, Yangyang Niu, Yuting Liu, Chunli Cui, Chen Yu

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in BMC nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Podocyte infolding glomerulopathy in a school-aged child.Pediatric nephrology (Berlin, Germany) · 2025
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xi LiuThe Department of Nephrology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Jieli HuangThe Department of Nephrology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Kun ZhangThe Department of Nephrology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Yangyang NiuThe Department of Nephrology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Yuting LiuThe Department of Nephrology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Chunli CuiThe Department of Nephrology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Chen YuThe Department of Nephrology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China. yuchen@tongji.edu.cn.
Tongji Hospital · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPodocytic infolding glomerulopathy (PIG) is a rare pathological change which was characterized by the microspheres or microtubular structures in the thickened glomerular basement membrane (GBM). Only a few dozen cases have been reported worldwide so far. Here we present a case of PIG with systemic lupus erythematosus. CASE PRESENTATION: A 61-year-old Chinese female was diagnosed with systemic lupus erythematosus with clinical manifestations of proteinuria, pleural effusion, seroperitoneum, anemia, leukopenia, thrombocytopenia, antinuclear antibody positive, and hypocomplementemia. She also had benign ovarian tumor and Epstein-Barr virus infection. Renal biopsy immunofluorescent staining showed IgM and C3 were granularly deposited along the capillary wall instead of typical "full house" features. Electron microscopy showed lots of microspheres structures were seen in the thickened GBM.

conclusionWe present a case of PIG in a patient with systemic lupus erythematosus. The mechanisms of PIG are unknown, but may be associated with connective tissue disease and podocyte injury.

Indexed as

FemaleGlomerular Basement MembraneHumansKidney DiseasesLupus Erythematosus, SystemicMiddle AgedEB virusOvarian tumorPodocytes,Systemic lupus erythematosusPodocytic infolding glomerulopathy

Identifiers

PMID34895156
PMCPMC8665562
OpenAlexW4200166596

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.