Evidence map›Paper›PMID 34895151›Full record

ArticleBMC gastroenterology2021

A case of primary intestinal lymphangiectasia with non-Hodgkin lymphoma.

Doudou Hu, Xianghua Cui, Wanlei Ren, Jian Zhang, Xin Guan, Xiangjun Jiang

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. CD5-positive diffuse large B-Cell lymphoma presenting with protein-losing enteropathy.Journal of clinical and experimental hematopathology : JCEH · 2026
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Doudou HuDepartment of Gastroenterology, Qingdao Municipal Hospital, Jiaozhou Road 1#, Qingdao, 266071, People's Republic of China.
Xianghua CuiDepartment of Gastroenterology, Qingdao Municipal Hospital, Jiaozhou Road 1#, Qingdao, 266071, People's Republic of China.
Wanlei RenDepartment of Traditional Chinese Medicine, Qingdao Central Hospital, Qingdao, 266042, People's Republic of China.
Jian ZhangDepartment of Gastroenterology, Qingdao Municipal Hospital, Jiaozhou Road 1#, Qingdao, 266071, People's Republic of China.
Xin GuanDepartment of Gastroenterology, Qingdao Municipal Hospital, Jiaozhou Road 1#, Qingdao, 266071, People's Republic of China.
Xiangjun JiangDepartment of Gastroenterology, Qingdao Municipal Hospital, Jiaozhou Road 1#, Qingdao, 266071, People's Republic of China. drjxj11@sohu.com.
Qingdao University · CN

Funding

National Natural Science Foundation of China 81800543
6 · The paper itself

Abstract

backgroundPrimary intestinal lymphangiectasia (PIL) is a rare protein-losing enteropathy characterized by the loss of proteins, lymphocytes, and immunoglobulins into the intestinal lumen. Increasing evidence has demonstrated an association between PIL and lymphoma. CASE PRESENTATION: A 54-year-old man with a 20-year history of abdominal distension and bilateral lower limb edema was admitted. Laboratory investigations revealed lymphopenia, hypoalbuminemia, decreased triglyceride and cholesterol level. Colonoscopy showed multiple smooth pseudo polyps in the ileocecal valve and terminal ileum and histological examination showed conspicuous dilation of the lymphatic channels in the mucosa and submucosa. A diagnosis of PIL was made. Three years later colonoscopy of the patient showed an intraluminal proliferative mass in the ascending colon and biopsy examination confirmed a malignant non-Hodgkin lymphoma. Then the patient was been underwent chemotherapy, and his clinical condition is satisfactory.

conclusionOur report supports the hypothesis that PIL is associated with lymphoma development.

Indexed as

Lymphangiectasis, IntestinalLymphoma, Non-HodgkinProtein-Losing EnteropathiesBiopsyHumansLymphocytesMaleMiddle AgedLymphomaPrimary intestinal lymphangiectasiaProtein-losing enteropathy

Identifiers

PMID34895151
PMCPMC8665534
OpenAlexW4200414368

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.