Evidence map›Paper›PMID 34894780›Full record

ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

Exploratory Evaluation of Rhythm Control by Dronedarone in Combination With Low-Dose Rivaroxaban, Warfarin, Antiplatelet, or None of the Antithrombotic Therapy in High-Risk Patients With Non-Permanent Atrial Fibrillation: A Retrospective Cohort Study.

Po-Lin Lin, Wei-Ru Chiou, Min-I Su, Chun-Che Huang, Feng-Ching Liao, Lawrence Yu-Min Liu, Jen-Yu Chuang, Chun-Yen Chen, Cheng-Ting Tsai, Jen-Yuan Kuo and 3 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Po-Lin Lin156934Hsinchu MacKay Memorial Hospital, Hsinchu, Taiwan.
Wei-Ru Chiou117127Taitung MacKay Memorial Hospital, Taitung, Taiwan.
Min-I Su117127Taitung MacKay Memorial Hospital, Taitung, Taiwan.
Chun-Che Huang54791I-Shou University, Kaohsiung, Taiwan.
Feng-Ching Liao145474MacKay Medical College, New Taipei, Taiwan.
Lawrence Yu-Min Liu156934Hsinchu MacKay Memorial Hospital, Hsinchu, Taiwan.
Jen-Yu Chuang36897MacKay Memorial Hospital, Taipei, Taiwan.
Chun-Yen Chen145474MacKay Medical College, New Taipei, Taiwan.
Cheng-Ting Tsai145474MacKay Medical College, New Taipei, Taiwan.
Jen-Yuan Kuo145474MacKay Medical College, New Taipei, Taiwan.
Ten-Fang Yang210861National Yang Ming Chiao Tung University, Hsinchu, Taiwan.
Yih-Jer Wu145474MacKay Medical College, New Taipei, Taiwan.
Ying-Hsiang Lee145474MacKay Medical College, New Taipei, Taiwan.ORCID https://orcid.org/0000-0002-1882-9664
Mackay Memorial Hospital · TWNational Yang Ming Chiao Tung University · TWI-Shou University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emerging data supports rhythm control to prevent major adverse cardiac events (MACE) in high-risk patients with atrial fibrillation (AF). Limited data demonstrated rivaroxaban 10 mg combining dronedarone seemed feasible. This study aimed at investigating clinical events in a dronedarone-treated cohort. This exploratory, retrospective chart review was conducted in nonpermanent AF patients receiving dronedarone for ≥ 3 months between 2009/1 and 2016/2. In Taiwan, dronedarone's labeled indication was strict to age ≥ 70 or 65 to 70 years with either hypertension, diabetes, prior stroke, or left atrium >50 mm. We divided all into 4 groups using antithrombotic strategies to evaluate the safety, effectiveness, and MACE endpoints. A total of 689 patients (mean CHA

Indexed as

AgedAtrial FibrillationDose-Response Relationship, DrugDronedaroneFemaleFibrinolytic AgentsFollow-Up StudiesHeart RateHumansMaleRetrospective StudiesRivaroxabanThromboembolismTreatment OutcomeWarfarinDronedaroneFibrinolytic AgentsRivaroxabanWarfarinatrial fibrillationdronedaronerhythm controlrivaroxaban

Identifiers

PMID34894780
PMCPMC8671665
OpenAlexW4200360020

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.