Evidence map›Paper›PMID 34894542›Full record

ReviewCurrent opinion in microbiology2022

Activation of the extracytoplasmic function σ factor σ

Theresa D Ho, Craig D Ellermeier

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current opinion in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Theresa D HoDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, 431 Newton Rd., Iowa City, IA 52242, USA.
Craig D EllermeierDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, 431 Newton Rd., Iowa City, IA 52242, USA; Graduate Program in Genetics, University of Iowa, Iowa City, IA 52242, USA. Electronic address: craig-ellermeier@uiowa.edu.
University of Iowa · US

Funding

Identification of daptomycin resistance mechanisms in Clostridioides difficileR01AI087834 · NIAID · UNIVERSITY OF IOWA · PI ELLERMEIER, CRAIG D · 2011 to 2025
$5.6M
NIAID NIH HHS R01 AI087834
6 · The paper itself

Abstract

Clostridioides difficile is naturally resistant to high levels of lysozyme an important component of the innate immune defense system. C. difficile encodes both constitutive as well as inducible lysozyme resistance genes. The inducible lysozyme resistance genes are controlled by an alternative σ factor σ

Indexed as

Clostridioides difficileSigma FactorBacterial ProteinsClostridioidesGene Expression Regulation, BacterialMuramidaseBacterial ProteinsMuramidaseSigma Factor

Identifiers

PMID34894542
PMCPMC8792214
OpenAlexW4200085389

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.