ReviewCurrent topics in behavioral neurosciences2022
Environmental Contributions to Anhedonia.
Review in Current topics in behavioral neurosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- The Differential Relation of Emotional, Physical, and Sexual Abuse Histories to Antidepressant Treatment Remission and Persistence of Anhedonia in Major Depression: A CAN-BIND-1 Report.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2023Trial
- Reward Deficits in Co-Occurring Social Anxiety and Depression: The Roles of Anhedonia, Boredom, Loneliness, and COVID-19 Social Restriction.Journal of clinical psychology · 2026Article
- The relationship between negative life events and anhedonia among patients with major depressive disorder: chain mediation of insomnia and dysfunctional attitudes.BMC psychiatry · 2026Article
- Neonatal striatal volume is associated with infant anhedonia.Journal of affective disorders · 2026Article
- Prevalence of anhedonia in women with deep endometriosis.Scientific reports · 2025Article
- Anhedonia is associated with higher functional connectivity between the nucleus accumbens and paraventricular nucleus of thalamus.Journal of affective disorders · 2024Article
- Sex moderates the effect of anhedonia on parietal alpha asymmetry.Journal of psychiatric research · 2024Article
- Childhood unpredictability is associated with increased risk for long- and short-term depression and anhedonia symptoms following combat deployment.Journal of mood and anxiety disorders · 2024Article
- Stressful Life Events and Reward Processing in Adults: Moderation by Depression and Anhedonia.Depression and anxiety · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anhedonia is a core feature of psychopathological conditions that have recent exposure to stress and trauma as central to their etiology. Indeed, evolutionary accounts of depression suggest that decreased motivation to pursue reward may be an adaptive strategy in the face of social stress, in particular, as it may serve to defuse interpersonal conflict. Through a review of rodent models and research with humans, we show that exposure to stress, particularly when it is chronic, repeated, and/or involves themes of social rejection or defeat, is consistently associated with reduced hedonic capacity ("liking"), motivation to pursue reward ("wanting"), and ability to learn from reward ("reward learning"). Further, across rodent and human research, there is evidence that females show greater stress-induced blunting of reward processing than males. In humans, this sex difference emerges most strongly when examining individual differences in the stress response rather than group differences in stress exposure. We discuss the implications of these findings for understanding the etiology of, and sex differences in, stress-related psychopathology, including depression and addiction.
Indexed as
Identifiers
34894350What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.