Evidence map›Paper›PMID 34894328›Full record

ArticleDiabetes therapy : research, treatment and education of diabetes and related disorders2022

Effects of Early Intensive Insulin Therapy on Endothelial Progenitor Cells in Patients with Newly Diagnosed Type 2 Diabetes.

Wei Zhang, Hongdong Wang, Fangcen Liu, Xiao Ye, Wenjuan Tang, Pengzi Zhang, Tianwei Gu, Dalong Zhu, Yan Bi

Erratum issued Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT03710811 (Observational Study of Drug Naive Type 2 Diabetes Receiving Continuous Subcutaneous Insulin Infusion Therapy), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03710811 unknown statusnot on this map

Observational Study of Drug Naive Type 2 Diabetes Receiving Continuous Subcutaneous Insulin Infusion Therapy

TypeobservationalSponsorThe Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolRan2017 to 2021Enrolled150ConditionsType 2 DiabetesArmsInsulin
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Wei Zhang *Department of Endocrinology, Nanjing Drum Tower Hospital Affiliated to Nanjing University Medical School, Nanjing, China.
Hongdong Wang *Department of Endocrinology, Nanjing Drum Tower Hospital Affiliated to Nanjing University Medical School, Nanjing, China.
Fangcen Liu *Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China.
Xiao YeDrum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China.
Wenjuan TangDepartment of Endocrinology, Nanjing Drum Tower Hospital Affiliated to Nanjing University Medical School, Nanjing, China.
Pengzi ZhangDepartment of Endocrinology, Nanjing Drum Tower Hospital Affiliated to Nanjing University Medical School, Nanjing, China.
Tianwei GuDepartment of Endocrinology, Nanjing Drum Tower Hospital Affiliated to Nanjing University Medical School, Nanjing, China.
Dalong ZhuDepartment of Endocrinology, Nanjing Drum Tower Hospital Affiliated to Nanjing University Medical School, Nanjing, China. zhudalong@nju.edu.cn.
Yan BiDepartment of Endocrinology, Nanjing Drum Tower Hospital Affiliated to Nanjing University Medical School, Nanjing, China. biyan@nju.edu.cn.ORCID http://orcid.org/0000-0003-3914-7854
Nanjing Drum Tower Hospital · CN

Funding

Jiangsu Provincial Key Medical Discipline ZDXKB2016012Key Project of Nanjing Clinical Medical Science, the Jiangsu Provincial Medical Talent ZDRCA2016062National Key Research and Development Program of China 2016YFC1304804National Key Research and Development Program of China 2017YFC1309605National Natural Science Foundation of China 81703294National Natural Science Foundation of China 81770819National Natural Science Foundation of China 81800719National Natural Science Foundation of China 81800752National Natural Science Foundation of China 81900787National Natural Science Foundation of China 81970689National Natural Science Foundation of China 81970704National Natural Science Foundation of China 82000735National Natural Science Foundation of China 82000775National Natural Science Foundation of China 82030026National Natural Science Foundation of China 82070837Six Talent Peaks Project of Jiangsu Province of China YY-086
6 · The paper itself

Abstract

aimThis study aimed to investigate the alteration of circulating CD34

methodsIn this study, 36 patients with newly diagnosed type 2 diabetes and 22 control subjects matched by age and gender were enrolled. All of the patients with diabetes received intensive insulin therapy. The number of EPCs was assessed by flow cytometry based on the expression of CD34, CD133, and kinase insert domain-containing receptor (KDR).

resultsLevels of circulating CD34

conclusionsThese results showed that type 2 diabetes is associated with an increase of circulating CD34 CLINICAL TRIAL NUMBER: NCT03710811.

Indexed as

Endothelial progenitor cellsInflammationType 2 diabetesVascular endothelial growth factor

Identifiers

PMID34894328
PMCPMC8991286
OpenAlexW4200392818

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.