Evidence map›Paper›PMID 34894298›Full record

ArticleInsights into imaging2021

Intensity of arterial structure acquired by Silent MRA estimates cerebral blood flow.

Zhen-An Hwang, Chia-Wei Li, Chien-Yuan Eddy Lin, Jyh-Horng Chen, Chia-Yuen Chen, Wing P Chan

Open access · goldAbstract read
In one paragraph

Article in Insights into imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 75% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Zhen-An HwangDepartment of Radiology, Wan Fang Hospital, Taipei Medical University, 111 Hsing Long Road, Section 3, Taipei 116, Taiwan.
Chia-Wei LiDepartment of Radiology, Wan Fang Hospital, Taipei Medical University, 111 Hsing Long Road, Section 3, Taipei 116, Taiwan.
Chien-Yuan Eddy LinGE Healthcare, Taipei, Taiwan.
Jyh-Horng ChenDepartment of Electrical Engineering, National Taiwan University, Taipei, Taiwan.
Chia-Yuen ChenDepartment of Radiology, Wan Fang Hospital, Taipei Medical University, 111 Hsing Long Road, Section 3, Taipei 116, Taiwan.
Wing P ChanDepartment of Radiology, Wan Fang Hospital, Taipei Medical University, 111 Hsing Long Road, Section 3, Taipei 116, Taiwan. wingchan@tmu.edu.tw.ORCID http://orcid.org/0000-0001-8322-6336
Wan Fang Hospital · TWNational Taiwan University · TWTaipei Medical University Hospital · TW

Funding

inter-agency research fund, wan fang hospital, taipei medical university 107-wf-swf-09wan fang hospital, taipei medical university 109-wf-eva-21
6 · The paper itself

Abstract

backgroundCerebral blood flow (CBF) and the morphology of the cerebral arteries are important for characterizing cerebrovascular disease. Silent magnetic resonance angiography (Silent MRA) is a MRA technique focusing on arterial structural delineation. This study was conducted to investigate the correlation between Silent MRA and CBF quantification, which has not yet been reported.

methodsBoth the Silent MRA and time-of-flight magnetic resonance angiography scans were applied in seventeen healthy participants to acquire the arterial structure and to find arterial intensities. Phase-contrast MRA (PC-MRA) was then used to perform the quantitative CBF measurement of 13 cerebral arteries. Due to different dataset baseline signal level of Silent MRA, the signal intensities of the selected 13 cerebral arteries were normalized to the selected ROIs of bilateral internal carotid arteries. The normalized signal intensities were used to determine the relationship between Silent MRA and CBF.

resultsThe image intensity distribution of arterial regions generated by Silent MRA showed similar laminar shape as the phase distribution by PC-MRA (correlation coefficient > 0.62). Moreover, in both the results of individual and group-leveled analysis, the intensity value of arterial regions by Silent MRA showed positively correlation with the CBF by PC-MRA. The coefficient of determination (R

conclusionsThis study demonstrates that Silent MRA provides valuable CBF information despite arterial structure, rendering it a potential tool for screening for cerebrovascular disease.

Indexed as

Blood flowBrainMagnetic resonance angiography (MRA)Magnetic resonance imaging (MRI)

Identifiers

PMID34894298
PMCPMC8665965
OpenAlexW4200207488

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.