Trial reportClinical research in cardiology : official journal of the German Cardiac Society2022
Cost-effectiveness of noninvasive telemedical interventional management in patients with heart failure: health economic analysis of the TIM-HF2 trial.
Trial report in Clinical research in cardiology : official journal of the German Cardiac Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Economic Evaluations of Digital Health Interventions for Patients With Heart Failure: Systematic Review.Journal of medical Internet research · 2024Pooled it
- [Utilization of routine data from different statutory health insurance funds: a practical report of experience from the TIM-HF2 study about data acquisition, validation, and processing].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2023Trial
- Identifying and Comparing Intervention Cost Components in Remote Patient Monitoring: A Scoping Review.PharmacoEconomics · 2026Article
- Clinical Impact of Digital Health Interventions with Educational Components for Patients with Heart Failure: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2026Review
- Review
- Non-Invasive Remote Monitoring in Heart Failure: Towards Wearable Devices and Artificial Intelligence Solutions : Short Title: Remote Monitoring and Wearable Devices in Heart Failure.Current heart failure reports · 2025Review
- Economic Evaluation Methodologies of Remote Patient Monitoring for Chronic Conditions: Scoping Review.Journal of medical Internet research · 2025Article
- The present and future of cardiological telemonitoring in Europe: a statement from seven European countries.Herzschrittmachertherapie & Elektrophysiologie · 2025Review
- Linkage of Clinical Trial Data to Routinely Collected Data Sources: A Scoping Review.JAMA network open · 2025Article
- Cost-effectiveness of a multidimensional post-discharge disease management program for heart failure patients-economic evaluation along a one-year observation period.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Article
- Effectiveness of Telemonitoring in Reducing Hospitalization and Associated Costs for Patients With Heart Failure in Finland: Nonrandomized Pre-Post Telemonitoring Study.JMIR mHealth and uHealth · 2024Article
- Remote management of worsening heart failure to avoid hospitalization in a real-world setting.ESC heart failure · 2023Article
- Digital Transformation in the Diagnostics and Therapy of Cardiovascular Diseases: Comprehensive Literature Review.JMIR cardio · 2023Review
- Healthcare costs of a telemonitoring programme for heart failure: indirect deterministic data linkage analysis.ESC heart failure · 2022Article
- Digital Technologies to Support Better Outcome and Experience of Care in Patients with Heart Failure.Current heart failure reports · 2022Review
- [Telemedicine in chronic heart failure-From clinical studies to standard care].Der Internist · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
Abstract
backgroundNoninvasive remote patient management (RPM) in patients with heart failure (HF) has been shown to reduce the days lost due to unplanned cardiovascular hospital admissions and all-cause mortality in the Telemedical Interventional Management in Heart Failure II trial (TIM-HF2). The health economic implications of these findings are the focus of the present analyses from the payer perspective. METHODS AND
resultsA total of 1538 participants of the TIM-HF2 randomized controlled trial were assigned to the RPM and Usual Care group. Health claims data were available for 1450 patients (n = 715 RPM group, n = 735 Usual Care group), which represents 94.3% of the original TIM-HF2 patient population, were linked to primary data from the study documentation and evaluated in terms of the health care cost, total cost (accounting for intervention costs), costs per day alive and out of hospital (DAOH), and cost per quality-adjusted life year (QALY). The average health care costs per patient year amounted to € 14,412 (95% CI 13,284-15,539) in the RPM group and € 17,537 (95% CI 16,179-18,894) in the UC group. RPM led to cost savings of € 3125 per patient year (p = 0.001). After including the intervention costs, a cost saving of € 1758 per patient year remained (p = 0.048).
conclusionThe additional noninvasive telemedical interventional management in patients with HF was cost-effective compared to standard care alone, since such intervention was associated with overall cost savings and superior clinical effectiveness.
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Registered trials
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