ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2022
A Survey of Chinese Pig Farms and Human Healthcare Isolates Reveals Separate Human and Animal Methicillin-Resistant Staphylococcus aureus Populations.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Evolutionary and Mobile Genetic Element Analysis of a Multidrug-Resistant ST398-MRSA-Vc Isolate from Ready-to-Eat Pork Products.Antibiotics (Basel, Switzerland) · 2026Article
- Environmental Fate, Soil Ecological Responses and Fruit Quality Impacts of Emerging Contaminants (Antibiotics) in Orchard Ecosystems: A Review.Molecules (Basel, Switzerland) · 2026Review
- Identification and characterization of a novel major facilitator superfamily (MFS) efflux pump conferring multidrug resistance inAntimicrobial agents and chemotherapy · 2025Article
- Antibacterial Activity and Mechanism ofPlants (Basel, Switzerland) · 2025Article
- Simple and accurate genomic classification model for distinguishing between human and pig Staphylococcus aureus.Communications biology · 2024Article
- Exploring the third-generation tetracycline resistance of multidrug-resistant livestock-associated methicillin-resistant Staphylococcus aureus ST9 across healthcare settings in China.The Journal of antimicrobial chemotherapy · 2023Article
- The Epidemiology of Animal-Associated Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2023Review
- The prevalence ofFrontiers in microbiology · 2023Article
- A review of new emerging livestock-associated methicillin-resistantVeterinary world · 2023Review
- Genomic epidemiology and characterization ofFrontiers in microbiology · 2023Article
- Development of a Real-Time Recombinase-Aided Amplification Method to Rapidly Detect Methicillin-ResistantMicroorganisms · 2022Article
- Molecular Mechanisms of Drug Resistance inInternational journal of molecular sciences · 2022Review
- Article
- Antimicrobial Resistance and Molecular Epidemiology ofPathogens (Basel, Switzerland) · 2022Article
- A Survey of Chinese Pig Farms and Human Healthcare Isolates Reveals Separate Human and Animal Methicillin-Resistant Staphylococcus aureus Populations.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Prevalence of Livestock-Associated MRSA ST398 in a Swine Slaughterhouse in Guangzhou, China.Frontiers in microbiology · 2022Article
Corrections and comments
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Authors and funding
29 authors.
Funding
Abstract
There has been increasing concern that the overuse of antibiotics in livestock farming is contributing to the burden of antimicrobial resistance in people. Farmed animals in Europe and North America, particularly pigs, provide a reservoir for livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA ST398 lineage) found in people. This study is designed to investigate the contribution of MRSA from Chinese pig farms to human infection. A collection of 483 MRSA are isolated from 55 farms and 4 hospitals in central China, a high pig farming density area. CC9 MRSA accounts for 97.2% of all farm isolates, but is not present in hospital isolates. ST398 isolates are found on farms and hospitals, but none of them formed part of the "LA-MRSA ST398 lineage" present in Europe and North America. The hospital ST398 MRSA isolate form a clade that is clearly separate from the farm ST398 isolates. Despite the presence of high levels of MRSA found on Chinese pig farms, the authors find no evidence of them spilling over to the human population. Nevertheless, the ST398 MRSA obtained from hospitals appear to be part of a widely distributed lineage in China. The new animal-adapted ST398 lineage that has emerged in China is of concern.
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