ArticleHuman brain mapping2022
Motor training-related brain reorganization in patients with cerebellar degeneration.
Article in Human brain mapping, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Brain Neuroplasticity Related to Lateral Ankle Ligamentous Injuries: A Systematic Review.Sports medicine (Auckland, N.Z.) · 2023Pooled it
- Pragmatic Feasibility Study Combining Cerebello-spinal Neuromodulation and Exercise in Spinocerebellar Ataxia Type 3: A 20-session Single-arm Protocol.Cerebellum (London, England) · 2025Trial
- Gait Adaptability Training Improves Gait in Spinocerebellar Ataxia Patients.Movement disorders clinical practice · 2026Article
- Feasibility of a smartphone application for remote use in spastic ataxias: an 8-week long-term PROSPAX study.Journal of neurology · 2025Article
- Long-Term Effects of Annual Intensive Rehabilitation in Patients with Hereditary Pure Cerebellar Ataxia: A 7-year Follow-up Study.Cerebellum (London, England) · 2025Article
- First Application of a Novel Brain Template: Motor Training Improves Cortico-cerebellar Connectivity in Cerebellar Ataxia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Differences in the Impact of Intensive Rehabilitation on Hereditary Ataxias and the Cerebellar Subtype of Multiple System Atrophy.Cerebellum (London, England) · 2024Article
- Gray matter atrophy and white matter lesions burden in delayed cognitive decline following carbon monoxide poisoning.Human brain mapping · 2024Article
- Improvement of upper limb function in post-stroke patients with motion feedback training-based combination therapy: a retrospective analysis of muscle activation and recovery dynamics.American journal of translational research · 2024Article
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- Motor training-related brain reorganization in patients with cerebellar degeneration.Human brain mapping · 2022Article
- SUITPy: A Python-based toolbox for the analysis of cerebellar functional and anatomical imaging data across the human lifespan.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cerebellar degeneration progressively impairs motor function. Recent research showed that cerebellar patients can improve motor performance with practice, but the optimal feedback type (visual, proprioceptive, verbal) for such learning and the underlying neuroplastic changes are unknown. Here, patients with cerebellar degeneration (N = 40) and age- and sex-matched healthy controls (N = 40) practiced single-joint, goal-directed forearm movements for 5 days. Cerebellar patients improved performance during visuomotor practice, but a training focusing on either proprioceptive feedback, or explicit verbal feedback and instruction did not show additional benefits. Voxel-based morphometry revealed that after training gray matter volume (GMV) was increased prominently in the visual association cortices of controls, whereas cerebellar patients exhibited GMV increase predominantly in premotor cortex. The premotor cortex as a recipient of cerebellar efferents appears to be an important hub in compensatory remodeling following damage of the cerebro-cerebellar motor system.
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