Evidence map›Paper›PMID 34893952›Full record

ArticleJournal of gastrointestinal cancer2023

Quality Indicators and Outcomes in a Prospective Cohort of Colorectal Cancer Patients.

José M Quintana, Ane Anton-Ladislao, Santiago Lázaro, Nerea Gonzalez, Marisa Bare, Nerea Fernandez de Larrea, Maximino Redondo, Antonio Escobar, Cristina Sarasqueta, Susana Garcia-Gutierrez and 3 more

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Journal of gastrointestinal cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02488161 (Risk Factors of Adverse Outcomes at Short and Medium Term, and Development of Predictive Models, in Patients With Colorectal Cancer. IRYSS-coordinated Multicenter Study), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02488161 completednot on this map

Risk Factors of Adverse Outcomes at Short and Medium Term, and Development of Predictive Models, in Patients With Colorectal Cancer. IRYSS-coordinated Multicenter Study

TypeobservationalSponsorHospital Galdakao-UsansoloRan2010 to 2015Enrolled2,600ConditionsColorectal CancerArmsNo intervention
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Patient-reported outcomes and measures applied in individuals undergoing colonoscopy surveillance for colorectal cancer: a scoping review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

José M QuintanaUnidad de Investigación, Hospital Galdakao-Usansolo, Barrio Labeaga s/n, 48960, Galdakao, Bizkaia, Spain. josemaria.quintanalopez@osakidetza.eus.ORCID http://orcid.org/0000-0003-2170-7876
Ane Anton-LadislaoUnidad de Investigación, Hospital Galdakao-Usansolo, Barrio Labeaga s/n, 48960, Galdakao, Bizkaia, Spain.
Santiago LázaroServicio de Cirugía General, Hospital Basurto, Bilbao, Bizkaia, Spain.
Nerea GonzalezUnidad de Investigación, Hospital Galdakao-Usansolo, Barrio Labeaga s/n, 48960, Galdakao, Bizkaia, Spain.
Marisa BareUnidad de Epidemiología Clínica, Corporacio Parc Tauli, Barcelona, Spain.
Nerea Fernandez de LarreaCentro Nacional de Epidemiología, ISCIII, Madrid, Spain.
Maximino RedondoUnidad de Investigación, Hospital Costa del Sol, Malaga, Spain.
Antonio EscobarUnidad de Investigación, Hospital Basurto, Bilbao, Bizkaia, Spain.
Cristina SarasquetaUnidad de Investigación, Hospital Donostia/BioDonostia, Donostia, Guipuzkoa, Spain.
Susana Garcia-GutierrezUnidad de Investigación, Hospital Galdakao-Usansolo, Barrio Labeaga s/n, 48960, Galdakao, Bizkaia, Spain.
Urko AguirreUnidad de Investigación, Hospital Galdakao-Usansolo, Barrio Labeaga s/n, 48960, Galdakao, Bizkaia, Spain.
Eduardo BrionesUDG Salud Publica, Distrito AP Sevilla, Sevilla, Spain.
For The Redissec-Caress/C C R Group
Centro de Investigación Biomédica en Red · ESHospital de Basurto · ESBiogipuzkoa Health Research Institute · ESCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESHospital Costa del Sol · ESInstituto de Salud Carlos III · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSome quality indicators of proper health care in patients with colorectal cancer have been established.

aimsOur goal was to evaluate the relationship between performing of certain procedures or treatments, included as quality indicators, and some outcomes of indicators in the follow-up of colorectal cancer patients.

methodsThis was a prospective cohort study of patients diagnosed with colorectal cancer that underwent surgery and were followed at 1, 2, 3, and 5 years. CT scanning, colonoscopy, chemotherapy, and radiotherapy were evaluated in relation to various clinical outcomes and PROM changes over 5 years. Multivariable generalized linear mixed models were used to evaluate their effect on mortality, complications, recurrence, and PROM changes (HAD, EQ-5D, EORTC-Q30) at the next follow-up.

resultsCT scanning or colonoscopy was related to a decrease in the risk of dying, while chemotherapy at a specified moment was related to an increased risk. In the case of recurrence, CT scanning and chemotherapy showed statistically increased the risk, while all the procedures and treatments influenced complications. Regarding PROM scales, CT scanning, colonoscopy, and radiotherapy showed statistically significant results with respect to an increase in anxiety and decrease in quality of life measured by the EORTC. However, undergoing radiotherapy at a specified moment increased depression levels, and overall, receiving radiotherapy decreased the quality of life of the patients, as measured by the EuroQol-5d.

conclusionsAfter adjustment for sociodemographic factors, comorbidities, and severity of the disease, performing certain quality indicators of proper health care in patients with colorectal cancer was related to less mortality but higher adverse outcomes.

trial registrationClinicalTrials.gov Identifier: NCT02488161.

Indexed as

Colorectal NeoplasmsQuality of LifeHumansProspective StudiesQuality Indicators, Health CareColorectal cancerOutcomesProspective cohortQuality indexQuality of life

Identifiers

PMID34893952
OpenAlexW4200342069

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.