Evidence map›Paper›PMID 34893825›Full record

ArticleFamily practice2022

Primary care and medication management characteristics among patients receiving office-based opioid treatment with buprenorphine.

Cindy Xinxin Du, Julia Shi, Jeanette M Tetrault, Lynn M Madden, Declan T Barry

Open access · hybridAbstract read
In one paragraph

Article in Family practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Cindy Xinxin DuYale University School of Medicine, New Haven, CT, United States.ORCID 0000-0001-6584-9046
Julia ShiDepartment of Internal Medicine, Yale University School of Medicine, New Haven, CT, United States.
Jeanette M TetraultDepartment of Internal Medicine, Yale University School of Medicine, New Haven, CT, United States.ORCID 0000-0001-7091-9213
Lynn M MaddenDepartment of Internal Medicine, Yale University School of Medicine, New Haven, CT, United States.
Declan T BarryThe APT Foundation Inc., New Haven, CT, United States.ORCID 0000-0001-6697-5220
Yale University · US

Funding

HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR): Research CentersRM1DA055310 · NIDA · YALE UNIVERSITY · PI BARRY, DECLAN T., BECKER, WILLIAM C · 2021 to 2025
$12.9M
The Collaboration Linking Opioid Use Disorder and Sleep ("CLOUDS") StudyU01HL150596 · NHLBI · YALE UNIVERSITY · PI BARRY, DECLAN T., REDEKER, NANCY S · 2019 to 2024
$5.1M
NIAAA Short-Term Training: Students in Health Professional SchoolsT35AA023760 · NIAAA · YALE UNIVERSITY · PI HERZOG, ERICA L, KRYSTAL, JOHN H. · 2017 to 2021
$314k
NHLBI NIH HHS U01 HL150596NIAAA NIH HHS T35 AA023760NIDA NIH HHS RM1 DA055310
6 · The paper itself

Abstract

backgroundOffice-based opioid treatment (OBOT) is an evidence-based treatment model for opioid use disorder (OUD) offered by both addiction and general primary care providers (PCPs). Calls exist for more PCPs to offer OBOT. Few studies have been conducted on the primary care characteristics of OBOT patients.

objectiveTo characterize medical conditions, medications, and treatment outcomes among patients receiving OBOT with buprenorphine for OUD, and to describe differences among patients by age and by time in care.

methodsThis study is a retrospective review of medical records on or before 4/29/2019 at an outpatient primary care clinic within a nonprofit addiction treatment setting. Inclusion criterion was all clinic patients actively enrolled in the OBOT program. Patients not prescribed buprenorphine or with no OBOT visits were excluded.

resultsOf 355 patients, 42.0% had another PCP. Common comorbid conditions included chronic pain and psychiatric diagnosis. Few patients had chronic viral hepatitis or HIV. Patients reported a median of 4 medications. Common medications were cardiovascular, antidepressant, and nonopioid pain agents. Older patients had a higher median number of medications. There was no significant difference in positive opioid urine toxicology (UT) based on age, chronic pain status, or psychoactive medications. Patients retained >1 year were less likely to have positive opioid UT.

conclusionClinical needs of many patients receiving OBOT are similar to those of the general population, supporting calls for PCPs to provide OBOT.

Indexed as

BuprenorphineChronic PainOpioid-Related DisordersAnalgesics, OpioidHumansMedication Therapy ManagementOpiate Substitution TreatmentPrimary Health CareAnalgesics, OpioidBuprenorphinebuprenorphinemedications for opioid use disorderopiate substitution treatmentopioid-related disorderspolypharmacyprimary health care

Identifiers

PMID34893825
PMCPMC8947790
OpenAlexW4200396911

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.