Evidence map›Paper›PMID 34893693›Full record

ArticleScientific reports2021

Efficient detection of aortic stenosis using morphological characteristics of cardiomechanical signals and heart rate variability parameters.

Arash Shokouhmand, Nicole D Aranoff, Elissa Driggin, Philip Green, Negar Tavassolian

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Arash ShokouhmandDepartment of Electrical and Computer Engineering, Stevens Institute of Technology, Hoboken, NJ, 07030, USA.
Nicole D AranoffDepartment of Cardiovascular Medicine, Mount Sinai Morningside Hospital, New York, NY, 10025, USA.
Elissa DrigginThe New York-Presbyterian Hospital, New York, NY, 10065, USA.
Philip GreenDepartment of Cardiovascular Medicine, Mount Sinai Morningside Hospital, New York, NY, 10025, USA.
Negar TavassolianDepartment of Electrical and Computer Engineering, Stevens Institute of Technology, Hoboken, NJ, 07030, USA. negar.tavassolian@stevens.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent research has shown promising results for the detection of aortic stenosis (AS) using cardio-mechanical signals. However, they are limited by two main factors: lacking physical explanations for decision-making on the existence of AS, and the need for auxiliary signals. The main goal of this paper is to address these shortcomings through a wearable inertial measurement unit (IMU), where the physical causes of AS are determined from IMU readings. To this end, we develop a framework based on seismo-cardiogram (SCG) and gyro-cardiogram (GCG) morphologies, where highly-optimized algorithms are designed to extract features deemed potentially relevant to AS. Extracted features are then analyzed through machine learning techniques for AS diagnosis. It is demonstrated that AS could be detected with 95.49-100.00% confidence. Based on the ablation study on the feature space, the GCG time-domain feature space holds higher consistency, i.e., 95.19-100.00%, with the presence of AS than HRV parameters with a low contribution of 66.00-80.00%. Furthermore, the robustness of the proposed method is evaluated by conducting analyses on the classification of the AS severity level. These analyses are resulted in a high confidence of 92.29%, demonstrating the reliability of the proposed framework. Additionally, game theory-based approaches are employed to rank the top features, among which GCG time-domain features are found to be highly consistent with both the occurrence and severity level of AS. The proposed framework contributes to reliable, low-cost wearable cardiac monitoring due to accurate performance and usage of solitary inertial sensors.

Indexed as

Heart RateAgedAged, 80 and overAlgorithmsAortic ValveAortic Valve StenosisData AnalysisElectrocardiographyFemaleHumansMaleModels, Theoretical

Identifiers

PMID34893693
PMCPMC8664843

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.