ArticleScientific reports2021
Antibacterial efficacy of non-thermal atmospheric plasma against Streptococcus mutans biofilm grown on the surfaces of restorative resin composites.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Clinical evaluation of cold plasma surface activation using different plasma systems on early implant stability: a randomized controlled within-patient trial.BMC oral health · 2026Trial
- Phytosphingosine disrupts dual-species oral biofilms and attenuates LPS-induced pro-inflammatory responses in human gingival fibroblasts.Scientific reports · 2026Article
- Cold Atmospheric Plasma in Pediatric Dentistry: A Paradigm Shift toward Antibiotic-free Minimally Invasive Care.International journal of clinical pediatric dentistry · 2026Review
- Piezoelectric cold atmospheric plasma inactivates dairy cattle bacteria and potentiates antibiotics in vitro.Applied microbiology and biotechnology · 2026Article
- Evaluation of Streptococcus mutans biofilm formation on fluoride-releasing materials used as pit and fissure sealants.European journal of oral sciences · 2025Article
- Effect of cold atmospheric plasma on common oral pathogenic microorganisms: a narrative review.Annals of medicine · 2025Review
- Impact of toothbrushing on aesthetic and mechanical properties of hydrophilic antibacterial coating materials for orthodontic clear retainers.Scientific reports · 2025Article
- Scaled-up non-thermal plasma-generating device Plasmatico enables effective and harmless disinfection of personal protective equipment.Scientific reports · 2025Article
- Multifunctional resin-matrix ceramic: synergistic mechanical-biological optimization and novel strategies for translational research.RSC advances · 2025Review
- Exploring the Efficacy of Low-Temperature Plasmas on Oral Biofilms: A Scoping Review.Medical sciences (Basel, Switzerland) · 2025Article
- The Effect of Dielectric Barrier Discharge Plasma onJournal of lasers in medical sciences · 2025Article
- Inactivation of Pseudovirus Expressing the D614G Spike Protein Mutation using Nitric Oxide-Plasma Activated Water.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Non-thermal atmospheric pressure plasma induces selective cancer cell apoptosis by modulating redox homeostasis.Cell communication and signaling : CCS · 2024Article
- Exploring the efficacy of in-vitro low-temperature plasma treatment on single and multispecies dental cariogenic biofilms.Scientific reports · 2024Article
- [Study on the sterilization effect of plasma jet and plasma activated water onSheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023Article
- Aurora Borealis in dentistry: The applications of cold plasma in biomedicine.Materials today. Bio · 2022Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to evaluate the antimicrobial efficacy of non-thermal atmospheric plasma (NTAP) against Streptococcus mutans biofilms. Resin discs were fabricated, wet-polished, UV sterilized, and immersed in water for monomer extraction (37 °C, 24 h). Biofilms of bioluminescent S. mutans strain JM10 was grown on resin discs in anaerobic conditions for (37 °C, 24 h). Discs were divided into seven groups: control (CON), 2% chlorhexidine (CHX), only argon gas 150 s (ARG) and four NTAP treatments (30 s, 90 s, 120 s, 150 s). NTAP was applied using a plasma jet device. After treatment, biofilms were analyzed through the counting of viable colonies (CFU), bioluminescence assay (BL), scanning electron microscopy (SEM), and polymerase chain reaction (PCR). All NTAP-treated biofilm yielded a significant CFU reduction when compared to ARG and CON. BL values showed that NTAP treatment for 90 s, 120 s or 150 s resulted in statistically significantly lower metabolic activity when compared to the other groups. CHX displayed the lowest means of CFU and BL. SEM showed significant morphological changes in NTAP-treated biofilm. PCR indicated damage to the DNA structure after NTAP treatment. NTAP treatment was effective in lowering the viability and metabolism of S. mutans in a time-dependent manner, suggesting its use as an intraoral surface-decontamination strategy.
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