Evidence map›Paper›PMID 34893665›Full record

ArticleScientific reports2021

Electronic case report forms generation from pathology reports by ARGO, automatic record generator for onco-hematology.

Gian Maria Zaccaria, Vito Colella, Simona Colucci, Felice Clemente, Fabio Pavone, Maria Carmela Vegliante, Flavia Esposito, Giuseppina Opinto, Anna Scattone, Giacomo Loseto and 13 more

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Gian Maria ZaccariaHematology and Cell Therapy Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco, 65, Bari, Italy. g.m.zaccaria@oncologico.bari.it.
Vito ColellaDepartment of Electrical and Information Engineering, Politecnico of Bari, Bari, Italy.
Simona ColucciDepartment of Electrical and Information Engineering, Politecnico of Bari, Bari, Italy.
Felice ClementeHematology and Cell Therapy Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco, 65, Bari, Italy.
Fabio PavoneHematology and Cell Therapy Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco, 65, Bari, Italy.
Maria Carmela VeglianteHematology and Cell Therapy Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco, 65, Bari, Italy.
Flavia EspositoHematology and Cell Therapy Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco, 65, Bari, Italy.
Giuseppina OpintoHematology and Cell Therapy Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco, 65, Bari, Italy.
Anna ScattonePathology Department, IRCCS Istituto Tumori 'Giovanni Paolo II', Bari, Italy.
Giacomo LosetoHematology and Cell Therapy Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco, 65, Bari, Italy.
Carla MinoiaHematology and Cell Therapy Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco, 65, Bari, Italy.
Bernardo RossiniHematology and Cell Therapy Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco, 65, Bari, Italy.
Angela Maria QuintoHematology and Cell Therapy Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco, 65, Bari, Italy.
Vito AngiulliClinical Engineering Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', Bari, Italy.
Luigi Alfredo GriecoDepartment of Electrical and Information Engineering, Politecnico of Bari, Bari, Italy.
Angelo FamaHematology, Azienda USL - IRCCS Di Reggio Emilia, Reggio Emilia, Italy.
Simone FerreroDivision of Hematology 1, AOU "Città Della Salute e Della Scienza di Torino", Torino, Italy.
Riccardo MoiaDivision of Hematology, Azienda Ospedaliero-Universitaria Maggiore Della Carità Di Novara, Novara, Italy.
Alice Di RoccoUnit of Hematology, Azienda Ospedaliero-Universitaria Policlinico Umberto I, Roma, Italy.
Francesca Maria QuagliaDepartment of Medicine, Section of Hematology, University of Verona, Verona, Italy.
Valentina TabanelliDivision of Diagnostic Haematopathology, European Institute of Oncology, IRCCS, Milano, Italy.
Attilio GuariniHematology and Cell Therapy Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco, 65, Bari, Italy.
Sabino CiavarellaHematology and Cell Therapy Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco, 65, Bari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The unstructured nature of Real-World (RW) data from onco-hematological patients and the scarce accessibility to integrated systems restrain the use of RW information for research purposes. Natural Language Processing (NLP) might help in transposing unstructured reports into standardized electronic health records. We exploited NLP to develop an automated tool, named ARGO (Automatic Record Generator for Onco-hematology) to recognize information from pathology reports and populate electronic case report forms (eCRFs) pre-implemented by REDCap. ARGO was applied to hemo-lymphopathology reports of diffuse large B-cell, follicular, and mantle cell lymphomas, and assessed for accuracy (A), precision (P), recall (R) and F1-score (F) on internal (n = 239) and external (n = 93) report series. 326 (98.2%) reports were converted into corresponding eCRFs. Overall, ARGO showed high performance in capturing (1) identification report number (all metrics > 90%), (2) biopsy date (all metrics > 90% in both series), (3) specimen type (86.6% and 91.4% of A, 98.5% and 100.0% of P, 92.5% and 95.5% of F, and 87.2% and 91.4% of R for internal and external series, respectively), (4) diagnosis (100% of P with A, R and F of 90% in both series). We developed and validated a generalizable tool that generates structured eCRFs from real-life pathology reports.

Indexed as

Electronic Health RecordsHematologyMedical OncologyResearch ReportDisease ManagementHumansNatural Language ProcessingWorkflow

Identifiers

PMID34893665
PMCPMC8664934

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.