Evidence map›Paper›PMID 34893628›Full record

ArticleNature communications2021

Divergent functionalization of aldehydes photocatalyzed by neutral eosin Y with sulfone reagents.

Jianming Yan, Haidi Tang, Eugene Jun Rong Kuek, Xiangcheng Shi, Chenguang Liu, Muliang Zhang, Jared L Piper, Shengquan Duan, Jie Wu

Abstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Engineering an Artificial Metalloenzyme for Efficient Photo-Enzymatic COAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
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  4. Article
  5. Article
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  7. Synthesis and Photocatalytic spMolecules (Basel, Switzerland) · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jianming Yan *Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore, 117543, Republic of Singapore.ORCID http://orcid.org/0000-0001-6376-134X
Haidi Tang *Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore, 117543, Republic of Singapore.
Eugene Jun Rong KuekDepartment of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore, 117543, Republic of Singapore.
Xiangcheng ShiDepartment of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore, 117543, Republic of Singapore.
Chenguang LiuDepartment of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore, 117543, Republic of Singapore.
Muliang ZhangDepartment of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore, 117543, Republic of Singapore. muliang0206@foxmail.com.ORCID http://orcid.org/0000-0002-0415-9444
Jared L PiperPfizer Worldwide Research and Development, Eastern Point Rd, Groton, CT, 06340, USA.
Shengquan DuanPfizer Worldwide Research and Development, Eastern Point Rd, Groton, CT, 06340, USA. shengquan.duan@pfizer.com.ORCID http://orcid.org/0000-0002-8126-2592
Jie WuDepartment of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore, 117543, Republic of Singapore. chmjie@nus.edu.sg.ORCID http://orcid.org/0000-0002-9865-180X

Funding

National Natural Science Foundation of China (National Science Foundation of China) 22071170Pfizer (Pfizer Inc.) R-143-000-B60-114
6 · The paper itself

Abstract

While aldehydes represent a classic class of electrophilic synthons, the corresponding acyl radicals are inherently nucleophilic, which exhibits umpolung reactivity. Generation of acyl radicals typically requires noble metal catalysts or excess oxidants to be added. Herein, we report a convenient and green approach to access acyl radicals, capitalizing on neutral eosin Y-enabled hydrogen atom transfer (HAT) photocatalysis with aldehydes. The generated acyl radicals underwent SOMOphilic substitutions with various functionalized sulfones (X-SO

Identifiers

PMID34893628
PMCPMC8664905

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.