ArticleNature communications2021
Influence of the chirality of carbon nanodots on their interaction with proteins and cells.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Impact of Proteins on the Cellular Uptake of Carbon Nanodots.ACS omega · 2025Article
- Carbon Dots for Nucleic Acid-Based Diagnostics and Therapeutics: Focus on Oxidative DNA Damage.International journal of molecular sciences · 2025Review
- The Protein Corona Paradox: Challenges in Achieving True Biomimetics in Nanomedicines.Biomimetics (Basel, Switzerland) · 2025Review
- Concepts and Approaches to Reduce or Avoid Protein Corona Formation on Nanoparticles: Challenges and Opportunities.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- One-step simultaneous liquid phase exfoliation-induced chirality in graphene and their chirality-mediated microRNA delivery.Materials advances · 2023Article
- Immunotoxicity of Carbon-Based Nanomaterials, Starring Phagocytes.International journal of molecular sciences · 2022Review
- Coronas of micro/nano plastics: a key determinant in their risk assessments.Particle and fibre toxicology · 2022Review
- Carbon Dots in Bioimaging, Biosensing and Therapeutics: A Comprehensive Review.Small science · 2022Article
- Nuclear Magnetic Resonance Reveals Molecular Species in Carbon Nanodot Samples Disclosing Flaws.Angewandte Chemie (International ed. in English) · 2022Article
- Kinetic Processes in Enzymatic Nanoreactors for In Vivo Detoxification.Biomedicines · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carbon nanodots with opposite chirality possess the same major physicochemical properties such as optical features, hydrodynamic diameter, and colloidal stability. Here, a detailed analysis about the comparison of the concentration of both carbon nanodots is carried out, putting a threshold to when differences in biological behavior may be related to chirality and may exclude effects based merely on differences in exposure concentrations due to uncertainties in concentration determination. The present study approaches this comparative analysis evaluating two basic biological phenomena, the protein adsorption and cell internalization. We find how a meticulous concentration error estimation enables the evaluation of the differences in biological effects related to chirality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.