ArticleNutrition, metabolism, and cardiovascular diseases : NMCD2022
The relationship between C-Reactive protein and mortality in adults with diabetes: Influences of demographic characteristics, lifestyle behaviors, and medications.
Article in Nutrition, metabolism, and cardiovascular diseases : NMCD, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Association Between Uric Acid to HDL-C Ratio and Liver Transaminase Abnormalities: Insights from a Large-Scale General Population Study.Medicina (Kaunas, Lithuania) · 2025Article
- Effect of carvacrol on diabetes-induced oxidative stress, fibrosis and apoptosis in testicular tissues of adult rats.Physiological research · 2025Article
- Application of the C-reactive protein-triglyceride glucose index in predicting the risk of new-onset diabetes in the general population aged 45 years and older: a national prospective cohort study.BMC endocrine disorders · 2025Article
- Association between serum C-reactive protein and low muscle mass among US adults: Results from NHANES 1999 to 2006.Clinics (Sao Paulo, Brazil) · 2025Article
- Dynamic changes in hs-CRP and risk of all-cause mortality among middle-aged and elderly adults: findings from a nationwide prospective cohort and mendelian randomization.Aging clinical and experimental research · 2024Article
- Preoperative risk factors for ileostomy-associated kidney injury in colorectal tumor surgery following ileostomy formation.International journal of colorectal disease · 2024Article
- Article
- Association of inflammatory score with all-cause and cardiovascular mortality in patients with metabolic syndrome: NHANES longitudinal cohort study.Frontiers in immunology · 2024Article
- Association of lung function with the risk of cardiovascular diseases and all-cause mortality in patients with diabetes: Results from NHANES III 1988-1994.Frontiers in cardiovascular medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
BACKGROUND AND
aimsThis study assesses the influence of demographic, lifestyle, and medication in the association between CRP and mortality in a national sample of adults with diabetes. METHODS AND
resultsCross-sectional study of data from 1999 to 2010 National Health and Nutrition Examination Survey (unweighted n = 3952; Weighted n = 19,064,710). Individuals were categorized as having diabetes if told by a provider they had diabetes, were taking insulin or other diabetes medications, or had a glycosylated hemoglobin A1c (HbA1c) ≥ 6.5%. CRP was classified into four categories: normal (≤0.1 mg/dL); moderate risk (0.11-0.3 mg/dL); high-risk (0.31-1.0 mg/dL); very high-risk (>1.0 mg/dL). Higher risk for mortality was associated with a very high-risk of CRP (HR = 1.88 (95% CI: 1.27-2.78), being a current (HR = 1.49 (95% CI: 1.10-2.01) or former (HR = 1.34 (95% CI: 1.03-1.73) smoker, and taking insulin (HR = 1.60 (95% CI: 1.25-2.05), taking anti-hypertensives (HR = 1.50 (95% CI: 1.22-1.85), and having co-morbidities such as cancer (HR = 1.32 (95% CI: 1.05-1.66) and hepatitis infection (HR = 1.76 (95% CI: 1.07-2.91), while taking Metformin (HR = 0.62 (95% CI: 0.50-0.76) had a lower risk of mortality.
conclusionIn this sample of adults with diabetes, demographic, lifestyle, and medication factors influenced the association between CRP and mortality. Interventions should focus on these factors to reduce mortality in adults with diabetes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.