ArticleHuman vaccines & immunotherapeutics2021
COVID-19 mRNA vaccine may trigger subacute thyroiditis.
Article in Human vaccines & immunotherapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- SARS-CoV-2 vaccine-associated subacute thyroiditis: insights from a systematic review.Journal of endocrinological investigation · 2022Pooled it
- Endocrine system after 2 years of COVID-19 vaccines: A narrative review of the literature.Frontiers in endocrinology · 2022Pooled it
- Thyroid Inconveniences With Vaccination Against SARS-CoV-2: The Size of the Matter. A Systematic Review.Frontiers in endocrinology · 2022Pooled it
- Review
- Neck Pain and Symptomatic Hypothyroidism: An Atypical Presentation of Subacute Thyroiditis.Cureus · 2024Article
- Subacute thyroiditis after receiving the COVID-19 vaccine.Respiratory medicine case reports · 2024Article
- Clinical Aspects in Subacute Thyroiditis: A Real-Life Study on 226 Cases in Greece Amid the COVID-19 Pandemic.Journal of clinical medicine · 2023Article
- COVID-19 vaccination and thyroiditis.Best practice & research. Clinical endocrinology & metabolism · 2023Review
- Insights into SARS-CoV-2-associated subacute thyroiditis: from infection to vaccine.Virology journal · 2023Review
- Subacute Thyroiditis Developing Within 2 Days of Vaccination Against COVID-19 with BNT162b2 mRNA.European journal of case reports in internal medicine · 2023Article
- Emerging trends and hot spots in subacute thyroiditis research from 2001 to 2022: A bibliometric analysis.Frontiers in endocrinology · 2023Article
- Investigating thyroid dysfunction in the context of COVID-19 infection.Annals of medicine and surgery (2012) · 2022Review
- Evaluation of metabolic changes in FDG PET/CT imaging after mRNA-based COVID-19 vaccination.Turkish journal of medical sciences · 2022Observational
- Type 1 diabetes mellitus following SARS-CoV-2 mRNA vaccination.Endocrine · 2022Article
- Thyroid dysfunction following vaccination with COVID-19 vaccines: a basic review of the preliminary evidence.Journal of endocrinological investigation · 2022Review
- Evaluation of the diagnostic features and clinical course of COVID-19 vaccine-associated subacute thyroiditis.Hormones (Athens, Greece) · 2022Article
- Article
- Orbital inflammatory disease following mRNA SARS-CoV-2 vaccine.Clinical case reports · 2022Article
- The New Entity of Subacute Thyroiditis amid the COVID-19 Pandemic: From Infection to Vaccine.Diagnostics (Basel, Switzerland) · 2022Review
- Two Case Reports of Subacute Thyroiditis after Receiving Vaccine for COVID-19.Case reports in endocrinology · 2022Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Subacute thyroiditis is the most common cause of painful thyroiditis, which usually occurs after an acute viral upper respiratory tract infection. Rare cases of subacute thyroiditis have been reported after administration of viral vaccines. Here, we report four cases of subacute thyroiditis after administration of the COVID-19 mRNA vaccine (Pfizer/BioNTech®). We describe the clinical, laboratory and imaging features of five cases of subacute thyroiditis after COVID-19 mRNA vaccine (Pfizer/BioNTech®). COVID-19 mRNA vaccine (Pfizer/BioNTech®)-associated subacute thyroiditis may present with clinical findings typical of classic subacute thyroiditis such as fever, neck pain, weakness, and tremor within a few days following vaccination. Subacute thyroiditis may be focal or may progress with diffuse bilateral involvement. Depending on the extent of subacute thyroiditis involvement, significant increases in acute-phase reactants can be observed. COVID-19 mRNA vaccine (Pfizer/BioNTech®) associated subacute thyroiditis responds quite well to non-steroidal anti-inflammatory therapy. Clinicians should be aware of the risk of developing subacute thyroiditis after vaccination.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.