Evidence map›Paper›PMID 34892993›Full record

ArticleWomen's health (London, England)

COVID-19 in pregnancy by race and ethnicity: Implications for development of a vaccination strategy.

Alice Pressman, Stephen H Lockhart, Joseph Wilcox, Kelly Smits, Joan Etzell, Sami Albeiroti, Michele DeRee, Christine Flaherty, Sheila Genolaga, Michelle Goodreau and 4 more

Open access · goldAbstract read
In one paragraph

Article in Women's health (London, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Auxiliary Screening COVID-19 by Serology.Frontiers in public health · 2022
    Pooled it
  2. Article
  3. Pregnancy and Diabetes Racial/Ethnicity Health Disparities in a Large Integrated Health System.Clinical diabetes : a publication of the American Diabetes Association · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Alice PressmanSutter Health Institute for Advancing Health Equity, Sutter Health, Sacramento, CA, USA.ORCID 0000-0003-2775-3275
Stephen H LockhartSutter Health Institute for Advancing Health Equity, Sutter Health, Sacramento, CA, USA.ORCID 0000-0002-1211-3817
Joseph WilcoxSutter Health Center for Health Systems Research, Sutter Health, Walnut Creek, CA, USA.
Kelly SmitsSutter Health Institute for Advancing Health Equity, Sutter Health, Sacramento, CA, USA.ORCID 0000-0001-8686-4173
Joan EtzellShared Laboratory, Sutter Health, Livermore, CA, USA.
Sami AlbeirotiShared Laboratory, Sutter Health, Livermore, CA, USA.
Michele DeReeSutter Medical Center, Sacramento, CA, USA.
Christine FlahertySutter Health, Sacramento, CA, USA.
Sheila GenolagaSutter Health Center for Health Systems Research, Sutter Health, Walnut Creek, CA, USA.
Michelle GoodreauSutter Health Center for Health Systems Research, Sutter Health, Walnut Creek, CA, USA.
Farah RefaiSutter Health Center for Health Systems Research, Sutter Health, Walnut Creek, CA, USA.
Alexandra RestallSutter Health Institute for Advancing Health Equity, Sutter Health, Sacramento, CA, USA.
Katarina Lanner-CusinAlta Bates Summit Medical Center, Berkeley, CA, USA.
Kristen Mj AzarSutter Health Institute for Advancing Health Equity, Sutter Health, Sacramento, CA, USA.ORCID 0000-0003-2801-3156
Sutter Health · USAlta Bates Summit Medical Center · USSutter Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCOVID-19 and associated morbidity and mortality has disproportionately affected minoritized populations. The epidemiology of spread of COVID-19 among pregnant women by race/ethnicity is not well described. Using data from a large healthcare system in California, we estimated prevalence and spread during pregnancy and recommend a vaccination approach based on minimizing adverse outcomes.

methodsPatients delivering at Sutter Health are tested (molecular) for COVID-19. These results were combined with antibody test results, using samples drawn at delivery. For each racial/ethnic group, we estimated prevalence of COVID-19, using logistic regression to adjust for known sociodemographic and comorbid risk factors. Testing for immunoglobulin G and immunoglobulin M provided insight into timing of infections.

resultsAmong 17,446 women delivering May-December, 460 (2.6%) tested positive (molecular). Hispanic women were at 2.6 times the odds of being actively infected as White women (odds ratio = 2.6, 95% confidence interval = 2.0-3.3). August and December were the highest risk periods for active infection (odds ratio = 3.5, 95% confidence interval = 2.1-5.7 and odds ratio = 6.1, 95% confidence interval = 3.8-9.9, compared with May, respectively). Among 4500 women delivering October-December, 425 (9.4%) had positive molecular or antibody tests, ranging from 4.0% (Asian) to 15.7% (Hispanic). Adjusting for covariables, compared with White patients, odds of infection was similar for Black and Asian patients, with Hispanic at 2.4 (1.8-3.3) times the odds.

conclusionCOVID-19 prevalence was higher among Hispanic women at delivery and in the last trimester than their White counterparts. Higher rates in Black patients are explained by other risk factors. Resources should be directed to increase vaccination rates among Hispanic women in early stages of pregnancy.

Indexed as

COVID-19EthnicityFemaleHispanic or LatinoHumansPregnancySARS-CoV-2VaccinationantibodiesCOVID-19COVID-19 disparitiesCOVID-19 vaccine strategyhealth equitypregnancy

Identifiers

PMID34892993
PMCPMC8669880
OpenAlexW4200062969

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.