Evidence map›Paper›PMID 34892486›Full record

ArticleAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference2021

Variation is the Norm: Brain State Dynamics Evoked By Emotional Video Clips.

Ashutosh Singh, Christiana Westlin, Hedwig Eisenbarth, Elizabeth A Reynolds Losin, Jessica R Andrews-Hanna, Tor D Wager, Ajay B Satpute, Lisa Feldman Barrett, Dana H Brooks, Deniz Erdogmus

Abstract read
In one paragraph

Article in Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ashutosh Singh
Christiana Westlin
Hedwig Eisenbarth
Elizabeth A Reynolds Losin
Jessica R Andrews-Hanna
Tor D Wager
Ajay B Satpute
Lisa Feldman Barrett
Dana H Brooks
Deniz Erdogmus

Funding

The Neural Bases of Placebo Effects and their Relation to Regulatory ProcessesR01MH076136 · NIMH · UNIVERSITY OF COLORADO · PI WAGER, TOR D. · 2007 to 2023
$8.5M
fMRI-based Biomarkers for Multiple Components of PainR01DA035484 · NIDA · UNIVERSITY OF COLORADO · PI WAGER, TOR D. · 2013 to 2017
$3.1M
The neural bases of placebo effects and their relation to regulatory processesR37MH076136 · NIMH · DARTMOUTH COLLEGE · PI TOR D. WAGER · 2024 to 2026
$2.4M
Psychological and brain mechanisms underlying disparities in opioid and non-opioid pain treatment decisionsK01DA045735 · NIDA · UNIVERSITY OF MIAMI CORAL GABLES · PI LOSIN, ELIZABETH R · 2018 to 2022
$861k
NIDA NIH HHS K01 DA045735NIDA NIH HHS R01 DA035484NIMH NIH HHS R01 MH076136NIMH NIH HHS R37 MH076136
6 · The paper itself

Abstract

For the last several decades, emotion research has attempted to identify a "biomarker" or consistent pattern of brain activity to characterize a single category of emotion (e.g., fear) that will remain consistent across all instances of that category, regardless of individual and context. In this study, we investigated variation rather than consistency during emotional experiences while people watched video clips chosen to evoke instances of specific emotion categories. Specifically, we developed a sequential probabilistic approach to model the temporal dynamics in a participant's brain activity during video viewing. We characterized brain states during these clips as distinct state occupancy periods between state transitions in blood oxygen level dependent (BOLD) signal patterns. We found substantial variation in the state occupancy probability distributions across individuals watching the same video, supporting the hypothesis that when it comes to the brain correlates of emotional experience, variation may indeed be the norm.

Indexed as

BrainEmotionsBrain MappingFearHumansOxygen Saturation

Identifiers

PMID34892486
PMCPMC8784974

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.