ArticleAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference2021
Electrode Spacing and Current Distribution in Electrical Stimulation of Peripheral Nerve: A Computational Modeling Study using Realistic Nerve Models.
Article in Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Transcutaneous Cervical Vagus Nerve Stimulation Improves Speech Comprehension in Noise: A Crossover, Placebo-Controlled Study.Neuromodulation : journal of the International Neuromodulation Society · 2025Trial
- Modeling strategies in non-invasive spinal stimulation: perspectives on state-of-the-art.Frontiers in human neuroscience · 2026Review
- Reduce electrical overload via threaded Chinese acupuncture in nerve electrical therapy.Bioactive materials · 2025Article
- Transcutaneous cervical vagus nerve stimulation improves speech comprehension in noise: A crossover, placebo-controlled study.bioRxiv : the preprint server for biology · 2025Article
- Toward Safety Protocols for Peripheral Nerve Stimulation (PNS): A Computational and Experimental Approach.Bioelectromagnetics · 2025Article
- Machine learning enables non-Gaussian investigation of changes to peripheral nerves related to electrical stimulation.Scientific reports · 2024Article
- Electrical Stimulation Induced Current Distribution in Peripheral Nerves Varies Significantly with the Extent of Nerve Damage: A Computational Study Utilizing Convolutional Neural Network and Realistic Nerve Models.International journal of neural systems · 2023Article
- Computational optimization of delivery parameters to guide the development of targeted Nasal spray.Scientific reports · 2023Article
- Electrical Stimulation Induced Current Distribution in Peripheral Nerves Varies Significantly with the Extent of Nerve Damage: A Computational Study Utilizing Convolutional Neural Network and Realistic Nerve Models.International Work-Conference on the Interplay between Natural and Artificial ComputationArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Electrical stimulation of peripheral nerves has long been used and proven effective in restoring function caused by disease or injury. Accurate placement of electrodes is often critical to properly excite the nerve and yield the desired outcome. Computational modeling is becoming an important tool that can guide the rapid development and optimization of such implantable neural stimulation devices. Here, we developed a heterogeneous very high-resolution computational model of a realistic peripheral nerve stimulated by a current source through cuff electrodes. We then calculated the current distribution inside the nerve and investigated the effect of electrodes spacing on current penetration. In the present study, we first describe model implementation and calibration; we then detail the methodology we use to calculate current distribution and apply it to characterize the effect of electrodes distance on current penetration. Our computational results indicate that when the source and return cuff electrodes are placed close to each other, the penetration depth in the nerve is shallower than the cases in which the electrode distance is larger. This study outlines the utility of the proposed computational methods and anatomically correct high-resolution models in guiding and optimizing experimental nerve stimulation protocols.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.