Evidence map›Paper›PMID 34892055›Full record

ArticleAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference2021

20-fold Accelerated 7T fMRI Using Referenceless Self-Supervised Deep Learning Reconstruction.

Omer Burak Demirel, Burhaneddin Yaman, Logan Dowdle, Steen Moeller, Luca Vizioli, Essa Yacoub, John Strupp, Cheryl A Olman, Kamil Ugurbil, Mehmet Akcakaya

Open access · greenAbstract read
In one paragraph

Article in Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. CONSISTENCY MODELS FOR FAST MRI USING REGULARIZATION BY DENOISING.Proceedings. IEEE International Symposium on Biomedical Imaging · 2026
    Article
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  3. Article
  4. Article
  5. Time-Embedded Algorithm Unrolling for Computational MRI.Advances in neural information processing systems · 2025
    Article
  6. Article
  7. CYCLE-CONSISTENT SELF-SUPERVISED LEARNING FOR IMPROVED HIGHLY-ACCELERATED MRI RECONSTRUCTION.Proceedings. IEEE International Symposium on Biomedical Imaging · 2024
    Article
  8. Review
  9. High-fidelity Database-free Deep Learning Reconstruction for Real-time Cine Cardiac MRI.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2023
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Omer Burak Demirel
Burhaneddin Yaman
Logan Dowdle
Steen Moeller
Luca Vizioli
Essa Yacoub
John Strupp
Cheryl A Olman
Kamil Ugurbil
Mehmet Akcakaya
University of Minnesota · USResonance Research (United States) · US

Funding

TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Gregory John Metzger, KAMIL UGURBIL · 2019 to 2026
$11.7M
Elementary Neuronal Ensembles to Whole Brain Networks: Ultrahigh Resolution Imaging of Function and Connectivity in Humans - SUPPLEMENTU01EB025144 · NIBIB · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2017 to 2022
$9.7M
Institutional Center Cores for Advanced NeuroimagingP30NS076408 · NINDS · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2020
$4.2M
Rapid Comprehensive Cardiac MRI Exam for Diagnosis of Coronary Artery DiseaseR01HL153146 · NHLBI · UNIVERSITY OF MINNESOTA · PI AKCAKAYA, MEHMET · 2020 to 2024
$2.5M
NHLBI NIH HHS R01 HL153146NIBIB NIH HHS P41 EB027061NIBIB NIH HHS U01 EB025144NINDS NIH HHS P30 NS076408
6 · The paper itself

Abstract

High spatial and temporal resolution across the whole brain is essential to accurately resolve neural activities in fMRI. Therefore, accelerated imaging techniques target improved coverage with high spatio-temporal resolution. Simultaneous multi-slice (SMS) imaging combined with in-plane acceleration are used in large studies that involve ultrahigh field fMRI, such as the Human Connectome Project. However, for even higher acceleration rates, these methods cannot be reliably utilized due to aliasing and noise artifacts. Deep learning (DL) reconstruction techniques have recently gained substantial interest for improving highly-accelerated MRI. Supervised learning of DL reconstructions generally requires fully-sampled training datasets, which is not available for high-resolution fMRI studies. To tackle this challenge, self-supervised learning has been proposed for training of DL reconstruction with only undersampled datasets, showing similar performance to supervised learning. In this study, we utilize a self-supervised physics-guided DL reconstruction on a 5-fold SMS and 4-fold in-plane accelerated 7T fMRI data. Our results show that our self-supervised DL reconstruction produce high-quality images at this 20-fold acceleration, substantially improving on existing methods, while showing similar functional precision and temporal effects in the subsequent analysis compared to a standard 10-fold accelerated acquisition.

Indexed as

ConnectomeDeep LearningBrainHumansImage Processing, Computer-AssistedMagnetic Resonance Imaging

Identifiers

PMID34892055
PMCPMC8923746
OpenAlexW3162880680

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.