Evidence map›Paper›PMID 34891207›Full record

ReviewHormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme2021

Effects of Lipid Overload on Heart in Metabolic Diseases.

An Yan, Guinan Xie, Xinya Ding, Yi Wang, Liping Guo

Open access · hybridAbstract readReview
In one paragraph

Review in Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  5. EV-Encapsulated Mitochondrial miRNAs: Enhancing Cardiomyocyte Bioenergetics.International journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

An Yan *Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Guinan Xie *Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Xinya DingTianjin University of Traditional Chinese Medicine, Tianjin, China.
Yi WangTianjin University of Traditional Chinese Medicine, Tianjin, China.
Liping GuoTianjin Academy of Traditional Chinese Medicine, Tianjin, China.
Tianjin University of Traditional Chinese Medicine · CN

Funding

2020YJSB196 Tianjin Postgraduate Research and Innovation Project
6 · The paper itself

Abstract

Metabolic diseases are often associated with lipid and glucose metabolism abnormalities, which increase the risk of cardiovascular disease. Diabetic cardiomyopathy (DCM) is an important development of metabolic diseases and a major cause of death. Lipids are the main fuel for energy metabolism in the heart. The increase of circulating lipids affects the uptake and utilization of fatty acids and glucose in the heart, and also affects mitochondrial function. In this paper, the mechanism of lipid overload in metabolic diseases leading to cardiac energy metabolism disorder is discussed.

Indexed as

Lipid MetabolismAnimalsDiabetic CardiomyopathiesEnergy MetabolismGlucoseHumansMetabolic DiseasesMyocardiumGlucose

Identifiers

PMID34891207
PMCPMC8664556
OpenAlexW4200373647

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.