ReviewBreast (Edinburgh, Scotland)2022
Adverse health effects after breast cancer up to 14 years after diagnosis.
Review in Breast (Edinburgh, Scotland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- The impact of mind-body exercise on female breast cancer patients-a systematic review and meta-analysis of randomized controlled trials.Frontiers in public health · 2025Pooled it
- Dance and Dietary Intervention Improves Metabolic Health, Fitness, and Quality of Life With Modest Gut Microbiota Shifts in Breast Cancer Patients With Obesity: A Pilot RCT.Cancer reports (Hoboken, N.J.) · 2026Trial
- Network analysis of quality of life and depression in a randomized breast cancer trial with ten-years follow-up.Scientific reports · 2026Trial
- Exercise training decreases Neuregulin-1 concentrations in HER2-positive breast cancer patients undergoing adjuvant trastuzumab: the CARDAPAC study.Breast cancer research and treatment · 2026Trial
- Supportive care needs of women with breast cancer in the Middle East and North Africa region: A scoping review.International journal of nursing studies advances · 2026Review
- Beyond surgical risk: Multidimensional predictors of postoperative arm morbidity after breast cancer treatment.Breast (Edinburgh, Scotland) · 2026Article
- Healthcare Professionals' Experiences and Perspectives on Self-Management Education for Breast Cancer Survivors in Australian Primary Care: A Qualitative Study.Nursing reports (Pavia, Italy) · 2026Article
- Health-Related Quality of Life in Lung Cancer Survivors: Sociodemographic, Clinical, and Psychosocial Modulators.Current oncology (Toronto, Ont.) · 2026Article
- Psychophysiological changes during breast cancer treatment: a longitudinal analysis of subjective and objective indicators.BMC women's health · 2026Article
- Long-term breast cancer survivors: experiences, needs, and proposals for person-centred care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Effects of a 12-Week Supervised Exercise Program on Quality of Life, Functional Capacity, and Biological Parameters in Women with Breast Cancer: A Prospective Pilot Program.Journal of clinical medicine · 2026Article
- Facilitators to the implementation of exercise into cancer care: a systematic review.Journal of cancer survivorship : research and practice · 2026Review
- Unmet Supportive Care Needs in Cancer Survivors in Spain: A Multicentre Cross-Sectional Study on Prevalence and Sociodemographic and Disease-Related Risk Factors.Current oncology (Toronto, Ont.) · 2025Article
- Promoting early detection of necrotizing soft tissue infection of the upper extremity in patients with history of breast cancer: a case report.BMC women's health · 2025Article
- Breast Cancer Information Grand Round for Survivorship (BIG-S) prospective cohort.European journal of epidemiology · 2025Article
- The Effects of Concurrent Training on Molecular, Functional, and Clinical Outcomes in Breast Cancer Survivors: A Pilot Study.Cancers · 2025Article
- Impact of diagnosis-to-treatment interval on mortality in patients with early-stage breast cancer: a retrospective nationwide Korean cohort.BMC women's health · 2025Article
- Advancing breast cancer rehabilitation: a novel tool for assessing physical morbidity risk.The oncologist · 2025Article
- Long-term health-related quality of life among adolescent and young adult breast cancer survivors.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Physical activity and incident cardiovascular disease in breast cancer survivors: the Pathways Study.JNCI cancer spectrum · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe number of breast cancer survivors increases, but information about long-term adverse health effects in breast cancer survivors is sparse. We aimed to get an overview of the health effects for which survivors visit their general practitioner up to 14 years after diagnosis.
methodsWe retrieved data on 11,671 women diagnosed with breast cancer in 2000-2016 and 23,242 age and sex matched controls from the PSCCR-Breast Cancer, a database containing data about cancer diagnosis, treatment and primary healthcare. We built Cox regression models for 685 health effects, with time until the health effect as the outcome and survivor/control and cancer treatment as predictors. Models were built separately for four age groups (aged 18/44, 45/59, 60/74 and 75/89) and two follow-up periods (1/4 and 5/14 years after diagnosis).
results229 health effects occurred statistically significantly more often in survivors than in controls (p < 0.05). Health effects varied by age, time since diagnosis and treatment, but coughing, respiratory and urinary infections, fatigue, sleep problems, osteoporosis and lymphedema were statistically significantly increased in breast cancer survivors. Osteoporosis and chest symptoms were associated with hormone therapy; respiratory and skin infections with chemotherapy and lymphedema and skin infections with axillary dissection.
conclusionsBreast cancer survivors may experience numerous adverse health effects up to 14 years after diagnosis. Insight in individual risks may assist healthcare professionals in managing patient expectations and improve monitoring, detection and treatment of adverse health effects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.