Evidence map›Paper›PMID 34890763›Full record

ArticleInternational journal of cardiology2022

Left atrial strain improves echocardiographic classification of diastolic function in patients with metabolic syndrome and overweight-obesity.

Angel M Alonso Gómez, Lucas Tojal Sierra, Noris Mora Mora, Estefanía Toledo, Alvaro Alonso, María Garrido Uriarte, Carolina Sorto Sanchez, María P Portillo, Luis López Rodriguez, Elena Escribano Arellano and 2 more

Abstract read
In one paragraph

Article in International journal of cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
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  9. A Review of the Roles and Limitations of Noninvasive Imaging Methods for Investigating Cardiovascular Disease in Individuals with Obesity.Medical science monitor : international medical journal of experimental and clinical research · 2022
    Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Angel M Alonso GómezBioaraba Health Research Institute, Osakidetza Basque Health Service, Araba University Hospital, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain; CIBER Physiopathology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute (ISCIII), Madrid, Spain. Electronic address: angelmaria.alonsogomez@osakidetza.eus.
Lucas Tojal SierraBioaraba Health Research Institute, Osakidetza Basque Health Service, Araba University Hospital, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain; CIBER Physiopathology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute (ISCIII), Madrid, Spain. Electronic address: lutojal@hotmail.com.
Noris Mora MoraBalearic Islands Health Research Institute, Cardiology Department, Son Espases University Hospital, Palma de Mallorca, Balearic Islands, Spain. Electronic address: marta.noris@ssib.es.
Estefanía ToledoCIBER Physiopathology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute (ISCIII), Madrid, Spain; Navarra Institute for Health Research (IdiSNA), Pamplona, Navarra, Spain; Department of Preventive Medicine and Public Health, University of Navarra, Pamplona, Navarra, Spain. Electronic address: etoledo@unav.es.
Alvaro AlonsoDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA. Electronic address: alvaro.alonso@emory.edu.
María Garrido UriarteBioaraba Health Research Institute, Osakidetza Basque Health Service, Araba University Hospital, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain. Electronic address: mgarur@hotmail.com.
Carolina Sorto SanchezBioaraba Health Research Institute, Osakidetza Basque Health Service, Araba University Hospital, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain; CIBER Physiopathology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute (ISCIII), Madrid, Spain. Electronic address: daisysorto2@yahoo.com.
María P PortilloBioaraba Health Research Institute, Osakidetza Basque Health Service, Araba University Hospital, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain; CIBER Physiopathology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute (ISCIII), Madrid, Spain; Nutrition and Obesity Group, Dept. Pharmacy and Food Science, Faculty of Pharmacy, University of the Basque Country (UPV/EHU), Lucio Lascaray Research Centre, Vitoria, Spain. Electronic address: mariapuy.portillo@ehu.eus.
Luis López RodriguezBalearic Islands Health Research Institute, Cardiology Department, Son Espases University Hospital, Palma de Mallorca, Balearic Islands, Spain. Electronic address: It_lr@hotmail.com.
Elena Escribano ArellanoCardiology Department, Hospital Complex of Navarra, Pamplona, Navarra, Spain. Electronic address: elesar@ono.com.
Helmut SchröderCIBER Physiopathology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute (ISCIII), Madrid, Spain; Cardiovascular Risk and Nutrition Research Group (CARIN), Hospital del Mar, Barcelona, Spain; Medical Research Institute (IMIM), Barcelona, Spain. Electronic address: hschroeder@imim.es.
Jordi Salas-SalvadóCIBER Physiopathology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute (ISCIII), Madrid, Spain; Human Nutrition Unit, Department of Biochemistry and Biotechnology, Faculty of Medicine and Health Sciences, Sant Joan de Reus University Hospital, IISPV, Rovira i Virgili University, c/Sant Llorenç 21, 43201 Reus, Spain. Electronic address: jordi.salas@urv.cat.

Funding

Effect of an Intensive Lifestyle Intervention on the Atrial Fibrillation SubstrateR01HL137338 · NHLBI · EMORY UNIVERSITY · PI ALONSO, ALVARO · 2018 to 2021
$2.8M
Mentoring in patient-oriented atrial fibrillation and cardiovascular researchK24HL148521 · NHLBI · EMORY UNIVERSITY · PI ALONSO, ALVARO · 2019 to 2023
$593k
NHLBI NIH HHS K24 HL148521NHLBI NIH HHS R01 HL137338
6 · The paper itself

Abstract

backgroundCurrent recommendations for echocardiographic assessment of diastolic function (2016 guidelines of the American Society of Echocardiography (ASE)/European Association of Cardiovascular Imaging (EACVI) in patients with metabolic syndrome and overweight/obesity result in a significant number of patients with indeterminate diastolic dysfunction (LVDD). The aim of this article is to study whether the use of the left atrial strain criterion (LALS) reduces the number of indeterminate patients.

methods229 patients were studied with a complete echocardiographic study that included left ventricular longitudinal strain (LVLS) analysis, LALS and a maximal ergospirometry test with assessment of oxygen uptake (VO

resultsThe mean age was 65 ± 5 years, 153 (67%) males, with a mean EF of 60 ± 5%. The mean LVLS was -19.4 ± 2% and the LALS Reservoir was 23.8 ± 7%. There were 140 patients who did not meet LVDD criteria and 82 who did meet the indeterminate LVDD criterion. When the left atrial volume index (LAVI) >34 ml/m

conclusionsThis study confirms the low prevalence of diastolic dysfunction in overweight/obese patients with metabolic syndrome. Adding left atrial strain criterion to the current recommendations significantly reduces the number of indeterminate patients by reclassifying them as normal.

Indexed as

Metabolic SyndromeVentricular Dysfunction, LeftAgedDiastoleEchocardiographyHeart AtriaHumansMaleMiddle AgedObesityOverweightStroke VolumeVentricular Function, LeftDiastolic dysfunctionDoppler echocardiographyExercise capacityLeft atrial strainMetabolic syndrome

Identifiers

PMID34890763
PMCPMC8980725

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.