ArticlePloS one2021
Mother-to-child transmission of HIV infection and its associated factors in the district of Bilene, Gaza Province-Mozambique.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 30 citations in OpenAlex.
- Factors associated with HIV infection among infants born to mothers with HIV in Blantyre, Malawi: a mixed methods study.BMC public health · 2026Article
- Baseline characteristics associated with mortality among children living with HIV initiating ART at a rural district HIV clinic of Mozambique.Scientific reports · 2026Article
- HIV-1 drug resistance among pregnant and breastfeeding mothers and its association with paediatric HIV infections in the Dolutegravir era in Uganda.The Journal of antimicrobial chemotherapy · 2026Article
- Cutting-edge developments in computer-aided anti-HIV drug design.Frontiers in immunology · 2026Review
- Analysis of Risk Factors for High versus Low HIV Exposure in Neonates and Development of a Predictive Nomogram Model.Infection and drug resistance · 2026Article
- Prevalence and factors associated with sero-conversion among HIV exposed infants receiving care at Lira regional referral hospital in Lira City: a cross-sectional study.BMC pediatrics · 2025Article
- "ProTeggiMI": Adherence to HIV Vertical Transmission Prevention Pathway in Remote Communities in Mozambique.Open forum infectious diseases · 2025Article
- Epidemiological, clinical, and biological profiles of People Living With HIV in the PMTCT department of Panzi hospital: a retrospective cohort study in Eastern DR. Congo.AIDS research and therapy · 2025Article
- Chemokine receptor type-5: a key regulator of immunity, disease pathogenesis, and emerging therapeutic target.Inflammopharmacology · 2025Review
- Mother-to-Child Transmission of Human Immunodeficiency Virus and Its Determinants: Lessons Learnt from the Test and Treat Strategy at a Regional Hospital in Cameroon.Turkish archives of pediatrics · 2025Article
- Prevalence and Predictors of Mother-to-Child Transmission of Human Immunodeficiency Virus (HIV) among HIV-exposed Infants.International journal of MCH and AIDS · 2025Article
- Article
- Factors associated with HIV testing among pregnant women in Rwanda: A nationwide cross-sectional survey.PLOS global public health · 2024Article
- Exploring Stigma Experience and Coping Strategies Among Women Living with HIV/AIDS in China: A Phenomenological Study.Psychology research and behavior management · 2024Article
- Change in HIV-related characteristics of children hospitalised with infectious diseases in Western Cape, South Africa, 2008-2021: a time trend analysis.Journal of the International AIDS Society · 2023Article
- HIV-Host Cell Interactions.Cells · 2023Review
- Association between service readiness and PMTCT cascade effectiveness: a 2018 cross-sectional analysis from Manica province, Mozambique.BMC health services research · 2022Article
- Clinical and Biological Risk Factors Associated with Increased Mother-to-Child Transmission of HIV in Two South-East HIV-AIDS Regional Centers in Romania.Medicina (Kaunas, Lithuania) · 2022Article
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMother-to-child transmission of HIV infection is a significant problem in Mozambique. This study aims to determine the risk factors associated with mother-to-child transmission of HIV in rural Mozambique.
methodsRetrospective case-control study in a rural area of Bilene District, on the coast of southern Mozambique, performed from January 2017 to June 2018. The analysis considered the clinical data of HIV exposed children with definitive HIV positive results and their respective infected mothers (cases), and the data of HIV exposed children with definitive HIV negative results and their respective infected mothers (controls) registered in At Risk Child Clinics from 1st January 2017 to 30th June 2018 at the Macia and Praia de Bilene health facilities in Bilene district, Gaza province-Mozambique.
resultsNinety pregnant women with HIV were involved in the study, including 30 who had transmitted the infection to their children and 60 who had not. Statistical analysis, adjusted for maternal age and gestational age at first antenatal care visit, showed that independent risk factors for transmission were gestational age at first visit (adjusted odds ratio [aOR] 1.19, 95% confidence interval [CI] 1.05-1.36), non-adherence to combination antiretroviral therapy (56.7% vs. 5%; aOR 14.12, 95% CI 3.15-63.41); a viral load of 1000 copies/mL or more (90% vs. 5%; aOR: 156, 95% CI 22.91-1,062) and female sex of the neonate (80% vs. 51.7%; aOR: 4.43, 95% CI 1.33-15.87).
conclusionA high viral load and non-adherence to antiretroviral therapy are important predictors of mother-to-child HIV transmission.
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